Product Information
HYDROCORTISONE 2.5% CREAM is a generic product labeled by Padagis Israel Pharmaceuticals Ltd, priced at $0.0995 per GM under NDC 45802000403. Its NADAC has been published 657 times since Nov 28, 2013.
Strength
25 mg/g
Manufacturer
Padagis Israel Pharmaceuticals LtdNDC
45802000403
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Last Updated
6/17/2026
Active Ingredients
HYDROCORTISONEApproval Type
Generic (ANDA)
FDA Application
ANDA085025On Market Since
3/31/2006
Pharmacological Classes
Price Statistics
The NADAC for HYDROCORTISONE 2.5% CREAM has been published 657 times since Nov 28, 2013, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0995 per GM |
|---|---|
| All-time high | $0.1222 (Aug 13, 2025) |
| All-time low | $0.0761 (Sep 21, 2022) |
| 52-week high | $0.1222 |
| 52-week low | $0.0995 |
| Median price | $0.0950 |
| Average price | $0.0979 |
| Largest weekly change | +22.6% (Feb 22, 2023) |
| Weeks tracked | 657 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 6 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 6 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 35% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of HYDROCORTISONE 2.5% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for HYDROCORTISONE 2.5% CREAM, manufactured by Padagis Israel Pharmaceuticals Ltd, is $0.0995 per GM (NDC 45802000403), effective Jun 24, 2026.
How has the price of HYDROCORTISONE 2.5% CREAM changed over time?
Over the history we have for it, the NADAC for HYDROCORTISONE 2.5% CREAM has held within roughly two percent of its current level. It has been tracked across 657 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for HYDROCORTISONE 2.5% CREAM?
Since Nov 28, 2013, the NADAC for HYDROCORTISONE 2.5% CREAM has ranged from a low of $0.0761 (Sep 21, 2022) to a high of $0.1222 (Aug 13, 2025), with a median of $0.0950 per GM.
Are there cheaper alternatives to HYDROCORTISONE 2.5% CREAM?
Yes. 6 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, HYDROCORTISONE 2.5% OINTMENT, is $0.0644 per GM — about 35% below HYDROCORTISONE 2.5% CREAM.
Who manufactures HYDROCORTISONE 2.5% CREAM?
HYDROCORTISONE 2.5% CREAM (NDC 45802000403) is labeled by Padagis Israel Pharmaceuticals Ltd, and CMS classifies it as a generic product.
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