Product Information

BUPROPION HCL XL 300 MG TABLET is a generic product labeled by Actavis Pharma, Inc., priced at $0.1115 per EA under NDC 45963014230. Its NADAC has been published 589 times since Mar 18, 2015.

BUPROPION HCL XL 300 MG TABLET

Bupropion Hydrochloride
$0.1115per EA

Strength

300 mg/1

NDC

45963014230

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Last Updated

6/17/2026

Active Ingredients

BUPROPION HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA077285

On Market Since

2/17/2015

Pharmacological Classes

Aminoketone
Dopamine Uptake Inhibitors
Increased Dopamine Activity
Increased Norepinephrine Activity
Norepinephrine Uptake Inhibitors

Price Statistics

The NADAC for BUPROPION HCL XL 300 MG TABLET has been published 589 times since Mar 18, 2015, and over the history we have for it it has declined 85.2%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1115 per EA
All-time high$0.7543 (Aug 12, 2015)
All-time low$0.1033 (Feb 18, 2026)
52-week high$0.1504
52-week low$0.1033
Median price$0.2394
Average price$0.3166
Largest weekly change-33.9% (Sep 18, 2019)
Weeks tracked589
Tracking sinceMar 18, 2015

Price History

1W

0.0%

1M

-3.4%

3M

+3.9%

6M

-11.5%

1Y

-25.9%

3Y

-35.5%

5Y

-45.5%

All

-85.2%

Generic Alternatives

The matcher finds 9 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 9 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUPROPION HCL XL 300 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL XL 300 MG TABLET, manufactured by Actavis Pharma, Inc., is $0.1115 per EA (NDC 45963014230), effective Jun 24, 2026.

How has the price of BUPROPION HCL XL 300 MG TABLET changed over time?

Over the history we have for it, the NADAC for BUPROPION HCL XL 300 MG TABLET has declined 85.2%. It has been tracked across 589 weekly CMS publications since Mar 18, 2015.

What are the highest and lowest recorded NADAC prices for BUPROPION HCL XL 300 MG TABLET?

Since Mar 18, 2015, the NADAC for BUPROPION HCL XL 300 MG TABLET has ranged from a low of $0.1033 (Feb 18, 2026) to a high of $0.7543 (Aug 12, 2015), with a median of $0.2394 per EA.

Are there cheaper alternatives to BUPROPION HCL XL 300 MG TABLET?

9 NADAC-published products share the same active ingredient, strength, and dosage form as BUPROPION HCL XL 300 MG TABLET, but none are currently priced below it.

Who manufactures BUPROPION HCL XL 300 MG TABLET?

BUPROPION HCL XL 300 MG TABLET (NDC 45963014230) is labeled by Actavis Pharma, Inc., and CMS classifies it as a generic product.