Product Information
EPIPEN 2-PAK 0.3 MG AUTO-INJCT is a brand product labeled by Viatris Specialty LLC, priced at $289.9600 per EA under NDC 49502050002. Its NADAC has been published 622 times since Nov 28, 2013.
FDA first approved this application on Dec 22, 1987. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.3 mg/.3mL
Manufacturer
Viatris Specialty LLCNDC
49502050002
Classification
Brand
Dosage Form
INJECTION
Route
INTRAMUSCULAR
Effective Date
11/20/2024
Active Ingredients
EPINEPHRINEApproval Type
New Drug (NDA)
FDA Application
NDA019430FDA Approved
12/22/1987
TE Code
AB
On Market Since
12/22/1987
Pharmacological Classes
Price Statistics
The NADAC for EPIPEN 2-PAK 0.3 MG AUTO-INJCT has been published 622 times since Nov 28, 2013, and over the history we have for it it has risen 99.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $289.9600 per EA |
|---|---|
| All-time high | $294.6936 (Jul 13, 2016) |
| All-time low | $145.7261 (Nov 28, 2013) |
| 52-week high | $289.9600 |
| 52-week low | $289.9600 |
| Median price | $292.1743 |
| Average price | $273.3161 |
| Largest weekly change | +14.9% (May 13, 2015) |
| Weeks tracked | 622 |
| Tracking since | Nov 28, 2013 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
0.0%
3Y
-1.0%
5Y
-0.0%
All
+99.0%
Last surveyed Nov 12, 2025 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 61% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of EPIPEN 2-PAK 0.3 MG AUTO-INJCT?
The current National Average Drug Acquisition Cost (NADAC) for EPIPEN 2-PAK 0.3 MG AUTO-INJCT, manufactured by Viatris Specialty LLC, is $289.9600 per EA (NDC 49502050002), effective Nov 12, 2025.
How has the price of EPIPEN 2-PAK 0.3 MG AUTO-INJCT changed over time?
Over the history we have for it, the NADAC for EPIPEN 2-PAK 0.3 MG AUTO-INJCT has risen 99.0%. It has been tracked across 622 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for EPIPEN 2-PAK 0.3 MG AUTO-INJCT?
Since Nov 28, 2013, the NADAC for EPIPEN 2-PAK 0.3 MG AUTO-INJCT has ranged from a low of $145.7261 (Nov 28, 2013) to a high of $294.6936 (Jul 13, 2016), with a median of $292.1743 per EA.
Are there cheaper alternatives to EPIPEN 2-PAK 0.3 MG AUTO-INJCT?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, EPINEPHRINE 0.3 MG AUTO-INJECT, is $112.9870 per EA — about 61% below EPIPEN 2-PAK 0.3 MG AUTO-INJCT.
Who manufactures EPIPEN 2-PAK 0.3 MG AUTO-INJCT?
EPIPEN 2-PAK 0.3 MG AUTO-INJCT (NDC 49502050002) is labeled by Viatris Specialty LLC, and CMS classifies it as a brand product.