Strength
375 mg/1
Manufacturer
AvPAKNDC
50268059515
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
NAPROXENApproval Type
Generic (ANDA)
FDA Application
ANDA075927On Market Since
2/11/2015
Pharmacological Classes
Price Statistics
The NADAC for NAPROXEN 375 MG TABLET has been published 450 times since Nov 15, 2017, and over the history we have for it it has declined 2.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0573 per EA |
|---|---|
| All-time high | $0.0808 (Jun 16, 2021) |
| All-time low | $0.0474 (Apr 17, 2024) |
| 52-week high | $0.0620 |
| 52-week low | $0.0573 |
| Median price | $0.0684 |
| Average price | $0.0674 |
| Largest weekly change | -28.8% (Apr 17, 2024) |
| Weeks tracked | 450 |
| Tracking since | Nov 15, 2017 |
Generic Alternatives
The matcher finds 9 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 9 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of NAPROXEN 375 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for NAPROXEN 375 MG TABLET, manufactured by AvPAK, is $0.0573 per EA (NDC 50268059515), effective Jun 24, 2026.
How has the price of NAPROXEN 375 MG TABLET changed over time?
Over the history we have for it, the NADAC for NAPROXEN 375 MG TABLET has declined 2.7%. It has been tracked across 450 weekly CMS publications since Nov 15, 2017.
What are the highest and lowest recorded NADAC prices for NAPROXEN 375 MG TABLET?
Since Nov 15, 2017, the NADAC for NAPROXEN 375 MG TABLET has ranged from a low of $0.0474 (Apr 17, 2024) to a high of $0.0808 (Jun 16, 2021), with a median of $0.0684 per EA.
Are there cheaper alternatives to NAPROXEN 375 MG TABLET?
9 NADAC-published products share the same active ingredient, strength, and dosage form as NAPROXEN 375 MG TABLET, but none are currently priced below it.
Who manufactures NAPROXEN 375 MG TABLET?
NAPROXEN 375 MG TABLET (NDC 50268059515) is labeled by AvPAK, and CMS classifies it as a generic product.
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