Product Information

CLOBETASOL 0.05% CREAM is a generic product labeled by Sun Pharmaceutical Industries Inc., priced at $0.1427 per GM under NDC 51672125803. Its NADAC has been published 665 times since Nov 28, 2013.

FDA first approved this application on Jul 8, 1996. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

CLOBETASOL 0.05% CREAM

Clobetasol Propionate
$0.1427per GM

Strength

.5 mg/g

NDC

51672125803

Classification

Generic

Dosage Form

CREAM

Route

TOPICAL

Effective Date

8/19/2026

Active Ingredients

CLOBETASOL PROPIONATE

Approval Type

Generic (ANDA)

FDA Application

ANDA074249

FDA Approved

7/8/1996

TE Code

AB1

On Market Since

7/8/1996

Pharmacological Classes

Corticosteroid Hormone Receptor Agonists
Corticosteroid

Price Statistics

The NADAC for CLOBETASOL 0.05% CREAM has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 48.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1427 per GM
All-time high$4.0266 (Nov 12, 2014)
All-time low$0.1063 (Feb 18, 2026)
52-week high$0.1504
52-week low$0.1063
Median price$0.6405
Average price$1.0064
Largest weekly change+1491.8% (Sep 10, 2014)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

-1.7%

1M

-1.7%

3M

+1.3%

6M

+34.2%

1Y

+4.8%

3Y

-35.1%

5Y

-77.7%

All

-48.1%

Generic Alternatives

The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 19% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of CLOBETASOL 0.05% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL 0.05% CREAM, manufactured by Sun Pharmaceutical Industries Inc., is $0.1427 per GM (NDC 51672125803), effective Aug 19, 2026.

How has the price of CLOBETASOL 0.05% CREAM changed over time?

Over the history we have for it, the NADAC for CLOBETASOL 0.05% CREAM has declined 48.1%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for CLOBETASOL 0.05% CREAM?

Since Nov 28, 2013, the NADAC for CLOBETASOL 0.05% CREAM has ranged from a low of $0.1063 (Feb 18, 2026) to a high of $4.0266 (Nov 12, 2014), with a median of $0.6405 per GM.

Are there cheaper alternatives to CLOBETASOL 0.05% CREAM?

Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CLOBETASOL 0.05% CREAM, is $0.1152 per GM — about 19% below CLOBETASOL 0.05% CREAM.

Who manufactures CLOBETASOL 0.05% CREAM?

CLOBETASOL 0.05% CREAM (NDC 51672125803) is labeled by Sun Pharmaceutical Industries Inc., and CMS classifies it as a generic product.