Product Information

ESTRADIOL-NORETH 0.5-0.1 MG TB is a generic product labeled by Breckenridge Pharmaceutical Inc., priced at $0.8829 per EA under NDC 51991062328. Its NADAC has been published 665 times since Nov 28, 2013.

FDA first approved this application on Apr 17, 2008. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

ESTRADIOL-NORETH 0.5-0.1 MG TB

Estradiol and Norethindrone Acetate
$0.8829per EA

Strength

.5; .1 mg/1; mg/1

NDC

51991062328

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA078324

FDA Approved

4/17/2008

TE Code

AB

On Market Since

6/9/2011

Pharmacological Classes

Estradiol Congeners
Estrogen Receptor Agonists
Estrogen
Progesterone Congeners
Progestin

Price Statistics

The NADAC for ESTRADIOL-NORETH 0.5-0.1 MG TB has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 65.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.8829 per EA
All-time high$3.3260 (Feb 11, 2015)
All-time low$0.4048 (Nov 20, 2024)
52-week high$0.9671
52-week low$0.6778
Median price$2.3523
Average price$2.0306
Largest weekly change+61.5% (Aug 21, 2024)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

-1.6%

1M

-1.6%

3M

+27.8%

6M

-8.7%

1Y

+11.6%

3Y

-1.6%

5Y

-56.1%

All

-65.6%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of ESTRADIOL-NORETH 0.5-0.1 MG TB?

The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL-NORETH 0.5-0.1 MG TB, manufactured by Breckenridge Pharmaceutical Inc., is $0.8829 per EA (NDC 51991062328), effective Aug 19, 2026.

How has the price of ESTRADIOL-NORETH 0.5-0.1 MG TB changed over time?

Over the history we have for it, the NADAC for ESTRADIOL-NORETH 0.5-0.1 MG TB has declined 65.6%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for ESTRADIOL-NORETH 0.5-0.1 MG TB?

Since Nov 28, 2013, the NADAC for ESTRADIOL-NORETH 0.5-0.1 MG TB has ranged from a low of $0.4048 (Nov 20, 2024) to a high of $3.3260 (Feb 11, 2015), with a median of $2.3523 per EA.

Are there cheaper alternatives to ESTRADIOL-NORETH 0.5-0.1 MG TB?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as ESTRADIOL-NORETH 0.5-0.1 MG TB in a comparable dosage form, but none are currently priced below it.

Who manufactures ESTRADIOL-NORETH 0.5-0.1 MG TB?

ESTRADIOL-NORETH 0.5-0.1 MG TB (NDC 51991062328) is labeled by Breckenridge Pharmaceutical Inc., and CMS classifies it as a generic product.