Product Information

XATMEP 2.5 MG/ML ORAL SOLUTION is a brand product labeled by Azurity Pharmaceuticals Inc., priced at $21.7635 per ML under NDC 52652200106. Its NADAC has been published 47 times since Sep 18, 2024.

FDA first approved this application on Apr 25, 2017.

The High Outlier badge above means this manufacturer's average price in the Methotrexate market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

XATMEP 2.5 MG/ML ORAL SOLUTION

Methotrexate
$21.7635per ML
High Outlier

Strength

2.5 mg/mL

NDC

52652200106

Classification

Brand

Dosage Form

SOLUTION

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

METHOTREXATE

Approval Type

New Drug (NDA)

FDA Application

NDA208400

FDA Approved

4/25/2017

On Market Since

5/1/2017

Pharmacological Classes

Folate Analog Metabolic Inhibitor
Folic Acid Metabolism Inhibitors

Price Statistics

The NADAC for XATMEP 2.5 MG/ML ORAL SOLUTION has been published 47 times since Sep 18, 2024, and over the history we have for it it has risen 12.3%. The table below summarizes its recorded NADAC range and movement.

Current price$21.7635 per ML
All-time high$21.7635 (Aug 19, 2026)
All-time low$19.3298 (Oct 23, 2024)
52-week high$21.7635
52-week low$21.7635
Median price$21.0695
Average price$20.4602
Largest weekly change+9.0% (Jan 15, 2025)
Weeks tracked47
Tracking sinceSep 18, 2024

Price History

1W

+3.3%

1M

+3.3%

3M

+3.3%

6M

+3.3%

1Y

+3.3%

3Y

N/A

5Y

N/A

All

+12.3%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Methotrexate market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Frequently asked questions

What is the NADAC price of XATMEP 2.5 MG/ML ORAL SOLUTION?

The current National Average Drug Acquisition Cost (NADAC) for XATMEP 2.5 MG/ML ORAL SOLUTION, manufactured by Azurity Pharmaceuticals Inc., is $21.7635 per ML (NDC 52652200106), effective Aug 19, 2026.

How has the price of XATMEP 2.5 MG/ML ORAL SOLUTION changed over time?

Over the history we have for it, the NADAC for XATMEP 2.5 MG/ML ORAL SOLUTION has risen 12.3%. It has been tracked across 47 weekly CMS publications since Sep 18, 2024.

What are the highest and lowest recorded NADAC prices for XATMEP 2.5 MG/ML ORAL SOLUTION?

Since Sep 18, 2024, the NADAC for XATMEP 2.5 MG/ML ORAL SOLUTION has ranged from a low of $19.3298 (Oct 23, 2024) to a high of $21.7635 (Aug 19, 2026), with a median of $21.0695 per ML.

Are there cheaper alternatives to XATMEP 2.5 MG/ML ORAL SOLUTION?

No other NADAC-published product currently shares the active ingredient and strength of XATMEP 2.5 MG/ML ORAL SOLUTION in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures XATMEP 2.5 MG/ML ORAL SOLUTION?

XATMEP 2.5 MG/ML ORAL SOLUTION (NDC 52652200106) is labeled by Azurity Pharmaceuticals Inc., and CMS classifies it as a brand product.