Therapeutic Classes/Folate Analog Metabolic Inhibitor

Folate Analog Metabolic Inhibitor

43 drugs across 19 manufacturers|28 Generic,15 Brand

The Folate Analog Metabolic Inhibitor class contains 43 NDCs from 19 manufacturers (28 generic, 15 brand), at an average NADAC of $136.52 per unit. Every drug, manufacturer, and price in this FDA-defined pharmacologic class is listed below.

Total Drugs

28G / 15B

Manufacturers

Avg $136.5235/unit

Avg 7d Change

+0.85%

Across 25 drugs with changes

7d Activity

23↑2↓18 flat

of 43 total drugs

Class Price Trend

Monthly average NADAC price per unit, split by generic and brand

Manufacturer Breakdown

19 manufacturers producing drugs in this therapeutic class(4 pricing outliers)

Accord Healthcare Inc.

4 drugs

$0.8270

avg/unit

Teva Women's Health, Inc.

Teva Parenteral Medicines, Inc.

3 drugs

$1.0501

avg/unit

Hikma Pharmaceuticals USA Inc.

2 drugs

$0.6974

avg/unit

Teva Pharmaceuticals USA Inc.

2 drugs

$0.1577

avg/unit

Sun Pharmaceutical Industries Inc.

2 drugs

$0.1577

avg/unit

Alembic Pharmaceuticals Inc.

2 drugs

$0.1577

avg/unit

Azurity Pharmaceuticals Inc.

Fresenius Kabi USA, LLC

1 drug

$3.1832

avg/unit

and 7 more manufacturers

Drug Portfolio

43 drugs total, 43 shown

Drug ↕	NDC	Price	7d Change ↕	Class	Market Outlier	Manufacturer ↕
RASUVO 7.5 MG/0.15 ML AUTOINJ methotrexate	59137050504	$960.2932 per ML	—	Brand	High Outlier	Medexus Pharma Inc.
RASUVO 10 MG/0.2 ML AUTOINJ methotrexate	59137051004	$721.8144 per ML	—	Brand	High Outlier	Medexus Pharma Inc.
RASUVO 12.5 MG/0.25 ML AUTOINJ methotrexate	59137051504	$574.8679 per ML	—	Brand	High Outlier	Medexus Pharma Inc.
OTREXUP 15 MG/0.4 ML AUTO-INJ methotrexate	54436001504	$484.2097 per ML	—	Brand	High Outlier	Antares Pharma, Inc.
OTREXUP 20 MG/0.4 ML AUTO-INJ methotrexate	54436002004	$480.8553 per ML	—	Brand	High Outlier	Antares Pharma, Inc.
RASUVO 15 MG/0.3 ML AUTOINJ methotrexate	59137052004	$480.0023 per ML	+0.36%	Brand	High Outlier	Medexus Pharma Inc.
OTREXUP 17.5 MG/0.4 ML AUTOINJ methotrexate	54436001704	$476.9597 per ML	—	Brand	High Outlier	Antares Pharma, Inc.
OTREXUP 25 MG/0.4 ML AUTO-INJ methotrexate	54436002504	$475.8075 per ML	—	Brand	High Outlier	Antares Pharma, Inc.
RASUVO 17.5 MG/0.35 ML AUTOINJ methotrexate	59137052504	$409.9292 per ML	—	Brand	High Outlier	Medexus Pharma Inc.
RASUVO 20 MG/0.4 ML AUTOINJ methotrexate	59137053004	$362.2851 per ML	-0.05%	Brand	High Outlier	Medexus Pharma Inc.
RASUVO 25 MG/0.5 ML AUTOINJ methotrexate	59137054004	$289.3650 per ML	+0.53%	Brand	High Outlier	Medexus Pharma Inc.
TREXALL 10 MG TABLET Methotrexate	51285036801	$48.1352 per EA	—	—	High Outlier	Teva Women's Health, Inc.
TREXALL 7.5 MG TABLET Methotrexate	51285036701	$36.2091 per EA	—	—	High Outlier	Teva Women's Health, Inc.
TREXALL 5 MG TABLET Methotrexate	51285036601	$24.0884 per EA	—	—	High Outlier	Teva Women's Health, Inc.
XATMEP 2.5 MG/ML ORAL SOLUTION Methotrexate	52652200106	$21.7635 per ML	—	Brand	High Outlier	Azurity Pharmaceuticals Inc.
METHOTREXATE 50 MG/2 ML VIAL Methotrexate	61703016105	$3.1832 per ML	+1.75%	Generic	—	Hospira Inc.
METHOTREXATE 50 MG/2 ML VIAL Methotrexate	61703035010	$3.1832 per ML	+1.75%	Generic	—	Hospira Inc.
METHOTREXATE 50 MG/2 ML VIAL Methotrexate	61703035038	$3.1832 per ML	+1.75%	Generic	—	Hospira Inc.
METHOTREXATE 250 MG/10 ML VIAL METHOTREXATE SODIUM	63323012310	$3.1832 per ML	+1.75%	Generic	High Outlier	Fresenius Kabi USA, LLC
METHOTREXATE 50 MG/2 ML VIAL Methotrexate	00703367101	$1.8033 per ML	+2.68%	Generic	—	Teva Parenteral Medicines, Inc.
METHOTREXATE 50 MG/2 ML VIAL Methotrexate	16729027730	$1.8033 per ML	+2.68%	Generic	—	Accord Healthcare Inc.
METHOTREXATE 50 MG/2 ML VIAL Methotrexate	00143951910	$1.2370 per ML	-0.08%	Generic	—	Hikma Pharmaceuticals USA Inc.
METHOTREXATE 250 MG/10 ML VIAL Methotrexate	00703367501	$0.7020 per ML	—	Generic	—	Teva Parenteral Medicines, Inc.
METHOTREXATE 250 MG/10 ML VIAL Methotrexate	16729027703	$0.7020 per ML	—	Generic	—	Accord Healthcare Inc.
METHOTREXATE 1 GRAM/40 ML VIAL Methotrexate	00703367801	$0.6450 per ML	—	Generic	—	Teva Parenteral Medicines, Inc.
METHOTREXATE 1 GRAM/40 ML VIAL Methotrexate	16729027735	$0.6450 per ML	—	Generic	—	Accord Healthcare Inc.
METHOTREXATE 1 GRAM/40 ML VIAL Methotrexate	61703040825	$0.6450 per ML	—	Generic	—	Hospira Inc.
METHOTREXATE 1 GRAM/40 ML VIAL Methotrexate	61703040841	$0.6450 per ML	—	Generic	—	Hospira Inc.
METHOTREXATE 2.5 MG TABLET Methotrexate Sodium	00054455025	$0.1577 per EA	+0.74%	Generic	—	Hikma Pharmaceuticals USA Inc.
METHOTREXATE 2.5 MG TABLET methotrexate	00378001401	$0.1577 per EA	+0.74%	Generic	—	Mylan Pharmaceuticals Inc.
METHOTREXATE 2.5 MG TABLET Methotrexate	00555057202	$0.1577 per EA	+0.74%	Generic	—	Teva Pharmaceuticals USA Inc.
METHOTREXATE 2.5 MG TABLET Methotrexate	00555057235	$0.1577 per EA	+0.74%	Generic	—	Teva Pharmaceuticals USA Inc.
METHOTREXATE 2.5 MG TABLET Methotrexate	00904714110	$0.1577 per EA	+0.74%	Generic	—	Major Pharmaceuticals
METHOTREXATE 2.5 MG TABLET Methotrexate	16729048601	$0.1577 per EA	+0.74%	Generic	—	Accord Healthcare Inc.
METHOTREXATE 2.5 MG TABLET Methotrexate Sodium	47335023583	$0.1577 per EA	+0.74%	Generic	—	Sun Pharmaceutical Industries Inc.
METHOTREXATE 2.5 MG TABLET Methotrexate Sodium	47335023596	$0.1577 per EA	+0.74%	Generic	—	Sun Pharmaceutical Industries Inc.
METHOTREXATE 2.5 MG TABLET methotrexate	51079067005	$0.1577 per EA	+0.74%	Generic	—	Mylan Institutional LLC
METHOTREXATE 2.5 MG TABLET Methotrexate	59651018201	$0.1577 per EA	+0.74%	Generic	—	Aurobindo Pharma Limited
METHOTREXATE 2.5 MG TABLET Methotrexate	62135077235	$0.1577 per EA	+0.74%	Generic	—	Chartwell RX LLC
METHOTREXATE 2.5 MG TABLET METHOTREXATE	62332073031	$0.1577 per EA	+0.74%	Generic	—	Alembic Pharmaceuticals Inc.
METHOTREXATE 2.5 MG TABLET METHOTREXATE	62332073036	$0.1577 per EA	+0.74%	Generic	—	Alembic Pharmaceuticals Inc.
METHOTREXATE 2.5 MG TABLET Methotrexate Sodium	64850033001	$0.1577 per EA	+0.74%	Generic	—	Elite Laboratories, Inc.
METHOTREXATE 2.5 MG TABLET Methotrexate	68382077501	$0.1577 per EA	+0.74%	Generic	—	Zydus Pharmaceuticals (USA) Inc.

Follow this class across the site

These links connect the therapeutic class page to the specific suppliers, markets, and trend surfaces that help users keep exploring.

Top supplier

Medexus Pharma Inc. manufacturer profile

Review the supplier with the strongest product footprint inside this therapeutic class.

Lead market

Methotrexate market page

Move from the therapeutic class into the molecule that appears most often in this class-specific portfolio.

Trend hub

Latest trend hub

Compare this class against the rest of the weekly NADAC trend surface.

Guide

Understanding NADAC pricing

Use the explainer when you need a plain-English refresher on how these class-level numbers are published and interpreted.

Frequently Asked Questions

How many drugs are in the Folate Analog Metabolic Inhibitor class?

The Folate Analog Metabolic Inhibitor class contains 43 NDCs from 19 manufacturers — 28 generic and 15 brand products.

What is the average price of Folate Analog Metabolic Inhibitor drugs?

The average NADAC for the Folate Analog Metabolic Inhibitor class is $136.5235 per unit across 43 NDCs.

Is generic cheaper than brand in the Folate Analog Metabolic Inhibitor class?

Among products priced per ML, the average generic NADAC in this class is $1.6585, versus $478.1794 for brand — brand products average about 288× the generic price.

Which manufacturers make Folate Analog Metabolic Inhibitor drugs?

19 manufacturers make drugs in the Folate Analog Metabolic Inhibitor class. Ranked by number of NDCs, the largest are Medexus Pharma Inc. (7), Hospira Inc. (5), Antares Pharma, Inc. (4), Accord Healthcare Inc. (4), Teva Women's Health, Inc. (3).

How has Folate Analog Metabolic Inhibitor pricing changed recently?

Over the past 7 days, 23 NDCs in this class rose and 2 fell, with a class-wide average change of +0.8%.