Product Information

OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET is a generic product labeled by Amneal Pharmaceuticals of New York LLC, priced at $0.2307 per EA under NDC 53746020405. Its NADAC has been published 515 times since Aug 17, 2016.

OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET

Oxycodone and Acetaminophen
$0.2307per EA
DEA Schedule CII

Strength

325; 10 mg/1; mg/1

NDC

53746020405

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Last Updated

6/17/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA040778

On Market Since

11/27/2007

Pharmacological Classes

Full Opioid Agonists
Opioid Agonist

Price Statistics

The NADAC for OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET has been published 515 times since Aug 17, 2016, and over the history we have for it it has declined 61.7%. The table below summarizes its recorded NADAC range and movement.

Current price$0.2307 per EA
All-time high$0.6026 (Sep 14, 2016)
All-time low$0.1580 (Sep 22, 2021)
52-week high$0.2716
52-week low$0.2292
Median price$0.2381
Average price$0.2687
Largest weekly change-22.1% (Nov 20, 2024)
Weeks tracked515
Tracking sinceAug 17, 2016

Price History

1W

0.0%

1M

+0.7%

3M

-3.1%

6M

-6.1%

1Y

-15.1%

3Y

+0.8%

5Y

+29.2%

All

-61.7%

Generic Alternatives

The matcher finds 12 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 10 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 22% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET, manufactured by Amneal Pharmaceuticals of New York LLC, is $0.2307 per EA (NDC 53746020405), effective Jun 24, 2026.

How has the price of OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET changed over time?

Over the history we have for it, the NADAC for OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET has declined 61.7%. It has been tracked across 515 weekly CMS publications since Aug 17, 2016.

What are the highest and lowest recorded NADAC prices for OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET?

Since Aug 17, 2016, the NADAC for OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET has ranged from a low of $0.1580 (Sep 22, 2021) to a high of $0.6026 (Sep 14, 2016), with a median of $0.2381 per EA.

Are there cheaper alternatives to OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET?

Yes. 12 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET, is $0.1796 per EA — about 22% below OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET.

Who manufactures OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET?

OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET (NDC 53746020405) is labeled by Amneal Pharmaceuticals of New York LLC, and CMS classifies it as a generic product.