Product Information

HYDROCHLOROTHIAZIDE 12.5 MG CP is a generic product labeled by Rising Pharma Holdings Inc., priced at $0.0279 per EA under NDC 57237000205. Its NADAC has been published 602 times since Feb 11, 2015.

FDA first approved this application on Sep 18, 2007. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

HYDROCHLOROTHIAZIDE 12.5 MG CP

Hydrochlorothiazide
$0.0279per EA

Strength

12.5 mg/1

NDC

57237000205

Classification

Generic

Dosage Form

CAPSULE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

HYDROCHLOROTHIAZIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA078164

FDA Approved

9/18/2007

TE Code

AB

On Market Since

9/19/2007

Pharmacological Classes

Increased Diuresis
Thiazide Diuretic
Thiazides

Price Statistics

The NADAC for HYDROCHLOROTHIAZIDE 12.5 MG CP has been published 602 times since Feb 11, 2015, and over the history we have for it it has declined 50.3%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0279 per EA
All-time high$0.0597 (Apr 15, 2015)
All-time low$0.0263 (Jul 17, 2024)
52-week high$0.0306
52-week low$0.0279
Median price$0.0360
Average price$0.0374
Largest weekly change+21.9% (Aug 21, 2024)
Weeks tracked602
Tracking sinceFeb 11, 2015

Price History

1W

-0.8%

1M

-0.8%

3M

-2.5%

6M

-8.4%

1Y

-8.7%

3Y

-9.1%

5Y

-20.4%

All

-50.3%

Generic Alternatives

The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of HYDROCHLOROTHIAZIDE 12.5 MG CP?

The current National Average Drug Acquisition Cost (NADAC) for HYDROCHLOROTHIAZIDE 12.5 MG CP, manufactured by Rising Pharma Holdings Inc., is $0.0279 per EA (NDC 57237000205), effective Aug 19, 2026.

How has the price of HYDROCHLOROTHIAZIDE 12.5 MG CP changed over time?

Over the history we have for it, the NADAC for HYDROCHLOROTHIAZIDE 12.5 MG CP has declined 50.3%. It has been tracked across 602 weekly CMS publications since Feb 11, 2015.

What are the highest and lowest recorded NADAC prices for HYDROCHLOROTHIAZIDE 12.5 MG CP?

Since Feb 11, 2015, the NADAC for HYDROCHLOROTHIAZIDE 12.5 MG CP has ranged from a low of $0.0263 (Jul 17, 2024) to a high of $0.0597 (Apr 15, 2015), with a median of $0.0360 per EA.

Are there cheaper alternatives to HYDROCHLOROTHIAZIDE 12.5 MG CP?

6 manufacturers publish a NADAC-priced product with the same active ingredient and strength as HYDROCHLOROTHIAZIDE 12.5 MG CP in a comparable dosage form, but none are currently priced below it.

Who manufactures HYDROCHLOROTHIAZIDE 12.5 MG CP?

HYDROCHLOROTHIAZIDE 12.5 MG CP (NDC 57237000205) is labeled by Rising Pharma Holdings Inc., and CMS classifies it as a generic product.