Product Information

GLYBURIDE-METFORMIN 2.5-500 MG is a generic product labeled by Rising Pharma Holdings Inc., priced at $0.1705 per EA under NDC 57237002405. Its NADAC has been published 638 times since Apr 9, 2014.

GLYBURIDE-METFORMIN 2.5-500 MG

Glyburide and Metformin Hydrochloride

$0.1705per EA

Strength

2.5; 500 mg/1; mg/1

Manufacturer

Rising Pharma Holdings Inc.

NDC

57237002405

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Last Updated

6/17/2026

Active Ingredients

GLYBURIDE; METFORMIN HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA077870

On Market Since

11/14/2007

Pharmacological Classes

Biguanide

Biguanides

Sulfonylurea Compounds

Sulfonylurea

Price Statistics

The NADAC for GLYBURIDE-METFORMIN 2.5-500 MG has been published 638 times since Apr 9, 2014, and over the history we have for it it has risen 92.2%. The table below summarizes its recorded NADAC range and movement.

Current price	$0.1705 per EA
All-time high	$0.2036 (Mar 11, 2026)
All-time low	$0.0337 (Dec 20, 2023)
52-week high	$0.2036
52-week low	$0.1216
Median price	$0.0557
Average price	$0.0694
Largest weekly change	+57.9% (Jan 17, 2024)
Weeks tracked	638
Tracking since	Apr 9, 2014

Price History

0.0%

+2.5%

-13.8%

-10.7%

+40.2%

+206.6%

+249.2%

All

+92.2%

Generic Alternatives

The matcher finds 2 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 2 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

2 alternatives • Same active ingredient

GLYBURIDE-METFORMIN 2.5-500 MG

Generic

65862008101•Aurobindo Pharma Limited

$0.1705

GLYBURIDE-METFORMIN 2.5-500 MG

Generic

57237002401•Rising Pharma Holdings Inc.

$0.1705

Frequently asked questions

What is the NADAC price of GLYBURIDE-METFORMIN 2.5-500 MG?

The current National Average Drug Acquisition Cost (NADAC) for GLYBURIDE-METFORMIN 2.5-500 MG, manufactured by Rising Pharma Holdings Inc., is $0.1705 per EA (NDC 57237002405), effective Jun 24, 2026.

How has the price of GLYBURIDE-METFORMIN 2.5-500 MG changed over time?

Over the history we have for it, the NADAC for GLYBURIDE-METFORMIN 2.5-500 MG has risen 92.2%. It has been tracked across 638 weekly CMS publications since Apr 9, 2014.

What are the highest and lowest recorded NADAC prices for GLYBURIDE-METFORMIN 2.5-500 MG?

Since Apr 9, 2014, the NADAC for GLYBURIDE-METFORMIN 2.5-500 MG has ranged from a low of $0.0337 (Dec 20, 2023) to a high of $0.2036 (Mar 11, 2026), with a median of $0.0557 per EA.

Are there cheaper alternatives to GLYBURIDE-METFORMIN 2.5-500 MG?

2 NADAC-published products share the same active ingredient, strength, and dosage form as GLYBURIDE-METFORMIN 2.5-500 MG, but none are currently priced below it.