Product Information

RANOLAZINE ER 500 MG TABLET is a generic product labeled by American Health Packaging, priced at $0.1609 per EA under NDC 60687054921. Its NADAC has been published 309 times since Sep 23, 2020.

FDA first approved this application on May 28, 2019. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The Low Outlier badge above means this manufacturer's average price in the Ranolazine market falls below Q1 − 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

RANOLAZINE ER 500 MG TABLET

Ranolazine
$0.1609per EA
Low Outlier

Strength

500 mg/1

NDC

60687054921

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

RANOLAZINE

Approval Type

Generic (ANDA)

FDA Application

ANDA210054

FDA Approved

5/28/2019

TE Code

AB

On Market Since

8/19/2020

Pharmacological Classes

Anti-anginal
Cytochrome P450 2D6 Inhibitors
Cytochrome P450 3A Inhibitors
Organic Cation Transporter 2 Inhibitors
P-Glycoprotein Inhibitors

Price Statistics

The NADAC for RANOLAZINE ER 500 MG TABLET has been published 309 times since Sep 23, 2020, and over the history we have for it it has declined 63.2%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1609 per EA
All-time high$0.4370 (Oct 14, 2020)
All-time low$0.1581 (Jul 22, 2026)
52-week high$0.1743
52-week low$0.1581
Median price$0.2321
Average price$0.2515
Largest weekly change+17.6% (Aug 21, 2024)
Weeks tracked309
Tracking sinceSep 23, 2020

Price History

1W

+1.7%

1M

+1.7%

3M

-4.1%

6M

-0.9%

1Y

-7.7%

3Y

-25.0%

5Y

-52.5%

All

-63.2%

Generic Alternatives

The matcher finds 12 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of RANOLAZINE ER 500 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for RANOLAZINE ER 500 MG TABLET, manufactured by American Health Packaging, is $0.1609 per EA (NDC 60687054921), effective Aug 19, 2026.

How has the price of RANOLAZINE ER 500 MG TABLET changed over time?

Over the history we have for it, the NADAC for RANOLAZINE ER 500 MG TABLET has declined 63.2%. It has been tracked across 309 weekly CMS publications since Sep 23, 2020.

What are the highest and lowest recorded NADAC prices for RANOLAZINE ER 500 MG TABLET?

Since Sep 23, 2020, the NADAC for RANOLAZINE ER 500 MG TABLET has ranged from a low of $0.1581 (Jul 22, 2026) to a high of $0.4370 (Oct 14, 2020), with a median of $0.2321 per EA.

Are there cheaper alternatives to RANOLAZINE ER 500 MG TABLET?

12 manufacturers publish a NADAC-priced product with the same active ingredient and strength as RANOLAZINE ER 500 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures RANOLAZINE ER 500 MG TABLET?

RANOLAZINE ER 500 MG TABLET (NDC 60687054921) is labeled by American Health Packaging, and CMS classifies it as a generic product.