Product Information
BUPROPION HCL 100 MG TABLET is a generic product labeled by Chartwell RX LLC, priced at $0.1129 per EA under NDC 62135072490. Its NADAC has been published 153 times since Nov 1, 2023.
FDA first approved this application on Aug 19, 2016. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
100 mg/1
Manufacturer
Chartwell RX LLCNDC
62135072490
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
BUPROPION HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA206975FDA Approved
8/19/2016
TE Code
AB
On Market Since
8/19/2016
Pharmacological Classes
Price Statistics
The NADAC for BUPROPION HCL 100 MG TABLET has been published 153 times since Nov 1, 2023, and over the history we have for it it has declined 18.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1129 per EA |
|---|---|
| All-time high | $0.1497 (Jun 12, 2024) |
| All-time low | $0.1035 (Nov 20, 2024) |
| 52-week high | $0.1247 |
| 52-week low | $0.1129 |
| Median price | $0.1258 |
| Average price | $0.1271 |
| Largest weekly change | -24.1% (Nov 20, 2024) |
| Weeks tracked | 153 |
| Tracking since | Nov 1, 2023 |
Generic Alternatives
The matcher finds 8 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Chartwell RX LLC manufacturer profile
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Drug market
Bupropion Hydrochloride market comparison
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Therapeutic class
Aminoketone class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of BUPROPION HCL 100 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL 100 MG TABLET, manufactured by Chartwell RX LLC, is $0.1129 per EA (NDC 62135072490), effective Sep 30, 2026.
How has the price of BUPROPION HCL 100 MG TABLET changed over time?
Over the history we have for it, the NADAC for BUPROPION HCL 100 MG TABLET has declined 18.3%. It has been tracked across 153 weekly CMS publications since Nov 1, 2023.
What are the highest and lowest recorded NADAC prices for BUPROPION HCL 100 MG TABLET?
Since Nov 1, 2023, the NADAC for BUPROPION HCL 100 MG TABLET has ranged from a low of $0.1035 (Nov 20, 2024) to a high of $0.1497 (Jun 12, 2024), with a median of $0.1258 per EA.
Are there cheaper alternatives to BUPROPION HCL 100 MG TABLET?
8 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BUPROPION HCL 100 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures BUPROPION HCL 100 MG TABLET?
BUPROPION HCL 100 MG TABLET (NDC 62135072490) is labeled by Chartwell RX LLC, and CMS classifies it as a generic product.