Product Information

PROMETHAZINE-DM 6.25-15 MG/5 ML SOLUTION is a generic product labeled by ANI Pharmaceuticals, Inc., priced at $0.0383 per ML under NDC 62559075816. Its NADAC has been published 84 times since Nov 27, 2024.

PROMETHAZINE-DM 6.25-15 MG/5 ML SOLUTION

Promethazine Hydrochloride and Dextromethorphan Hydrobromide
$0.0383per ML

Strength

15; 6.25 mg/5mL; mg/5mL

NDC

62559075816

Classification

Generic

Dosage Form

SOLUTION

Route

ORAL

Last Updated

6/17/2026

Approval Type

Authorized Generic (NDA)

FDA Application

NDA011265

On Market Since

9/5/2024

Pharmacological Classes

Phenothiazine
Phenothiazines
Sigma-1 Agonist
Sigma-1 Receptor Agonists
Uncompetitive N-methyl-D-aspartate Receptor Antagonist
Uncompetitive NMDA Receptor Antagonists

Price Statistics

The NADAC for PROMETHAZINE-DM 6.25-15 MG/5 ML SOLUTION has been published 84 times since Nov 27, 2024, and over the history we have for it it has risen 30.8%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0383 per ML
All-time high$0.0487 (Jun 11, 2025)
All-time low$0.0293 (Nov 27, 2024)
52-week high$0.0487
52-week low$0.0383
Median price$0.0428
Average price$0.0416
Largest weekly change+17.8% (Dec 18, 2024)
Weeks tracked84
Tracking sinceNov 27, 2024

Price History

1W

0.0%

1M

-0.5%

3M

-2.5%

6M

-12.4%

1Y

-21.2%

3Y

N/A

5Y

N/A

All

+30.8%

Generic Alternatives

The matcher finds 5 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 5 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of PROMETHAZINE-DM 6.25-15 MG/5 ML SOLUTION?

The current National Average Drug Acquisition Cost (NADAC) for PROMETHAZINE-DM 6.25-15 MG/5 ML SOLUTION, manufactured by ANI Pharmaceuticals, Inc., is $0.0383 per ML (NDC 62559075816), effective Jul 1, 2026.

How has the price of PROMETHAZINE-DM 6.25-15 MG/5 ML SOLUTION changed over time?

Over the history we have for it, the NADAC for PROMETHAZINE-DM 6.25-15 MG/5 ML SOLUTION has risen 30.8%. It has been tracked across 84 weekly CMS publications since Nov 27, 2024.

What are the highest and lowest recorded NADAC prices for PROMETHAZINE-DM 6.25-15 MG/5 ML SOLUTION?

Since Nov 27, 2024, the NADAC for PROMETHAZINE-DM 6.25-15 MG/5 ML SOLUTION has ranged from a low of $0.0293 (Nov 27, 2024) to a high of $0.0487 (Jun 11, 2025), with a median of $0.0428 per ML.

Are there cheaper alternatives to PROMETHAZINE-DM 6.25-15 MG/5 ML SOLUTION?

5 NADAC-published products share the same active ingredient, strength, and dosage form as PROMETHAZINE-DM 6.25-15 MG/5 ML SOLUTION, but none are currently priced below it.

Who manufactures PROMETHAZINE-DM 6.25-15 MG/5 ML SOLUTION?

PROMETHAZINE-DM 6.25-15 MG/5 ML SOLUTION (NDC 62559075816) is labeled by ANI Pharmaceuticals, Inc., and CMS classifies it as a generic product.