Product Information
PROMETHAZINE-DM 6.25-15 MG/5 ML SOLUTION is a generic product labeled by Amneal Pharmaceuticals LLC, priced at $0.0383 per ML under NDC 65162068090. Its NADAC has been published 321 times since May 6, 2020.
The High Outlier badge above means this manufacturer's average price in the Promethazine Hydrochloride and Dextromethorphan Hydrobromide market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
PROMETHAZINE-DM 6.25-15 MG/5 ML SOLUTION
Promethazine Hydrochloride and Dextromethorphan HydrobromideStrength
15; 6.25 mg/5mL; mg/5mL
Manufacturer
Amneal Pharmaceuticals LLCNDC
65162068090
Classification
Generic
Dosage Form
SOLUTION
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
DEXTROMETHORPHAN HYDROBROMIDE; PROMETHAZINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA090575On Market Since
3/4/2011
Pharmacological Classes
Price Statistics
The NADAC for PROMETHAZINE-DM 6.25-15 MG/5 ML SOLUTION has been published 321 times since May 6, 2020, and over the history we have for it it has declined 38.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0383 per ML |
|---|---|
| All-time high | $0.0669 (Dec 16, 2020) |
| All-time low | $0.0293 (Nov 20, 2024) |
| 52-week high | $0.0487 |
| 52-week low | $0.0383 |
| Median price | $0.0457 |
| Average price | $0.0498 |
| Largest weekly change | -29.1% (Nov 20, 2024) |
| Weeks tracked | 321 |
| Tracking since | May 6, 2020 |
Generic Alternatives
The matcher finds 6 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 6 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of PROMETHAZINE-DM 6.25-15 MG/5 ML SOLUTION?
The current National Average Drug Acquisition Cost (NADAC) for PROMETHAZINE-DM 6.25-15 MG/5 ML SOLUTION, manufactured by Amneal Pharmaceuticals LLC, is $0.0383 per ML (NDC 65162068090), effective Jun 24, 2026.
How has the price of PROMETHAZINE-DM 6.25-15 MG/5 ML SOLUTION changed over time?
Over the history we have for it, the NADAC for PROMETHAZINE-DM 6.25-15 MG/5 ML SOLUTION has declined 38.9%. It has been tracked across 321 weekly CMS publications since May 6, 2020.
What are the highest and lowest recorded NADAC prices for PROMETHAZINE-DM 6.25-15 MG/5 ML SOLUTION?
Since May 6, 2020, the NADAC for PROMETHAZINE-DM 6.25-15 MG/5 ML SOLUTION has ranged from a low of $0.0293 (Nov 20, 2024) to a high of $0.0669 (Dec 16, 2020), with a median of $0.0457 per ML.
Are there cheaper alternatives to PROMETHAZINE-DM 6.25-15 MG/5 ML SOLUTION?
6 NADAC-published products share the same active ingredient, strength, and dosage form as PROMETHAZINE-DM 6.25-15 MG/5 ML SOLUTION, but none are currently priced below it.
Who manufactures PROMETHAZINE-DM 6.25-15 MG/5 ML SOLUTION?
PROMETHAZINE-DM 6.25-15 MG/5 ML SOLUTION (NDC 65162068090) is labeled by Amneal Pharmaceuticals LLC, and CMS classifies it as a generic product.
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