Product Information

CHLORTHALIDONE 25 MG TABLET is a generic product labeled by Rising Pharma Holdings Inc., priced at $0.0840 per EA under NDC 64980059910. Its NADAC has been published 86 times since Jan 1, 2025.

FDA first approved this application on Feb 9, 2022. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

CHLORTHALIDONE 25 MG TABLET

Chlorthalidone
$0.0840per EA

Strength

25 mg/1

NDC

64980059910

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

CHLORTHALIDONE

Approval Type

Generic (ANDA)

FDA Application

ANDA211320

FDA Approved

2/9/2022

TE Code

AB

On Market Since

10/23/2024

Pharmacological Classes

Increased Diuresis
Thiazide-like Diuretic

Price Statistics

The NADAC for CHLORTHALIDONE 25 MG TABLET has been published 86 times since Jan 1, 2025, and over the history we have for it it has risen 9.3%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0840 per EA
All-time high$0.0901 (May 13, 2026)
All-time low$0.0745 (Jan 22, 2025)
52-week high$0.0901
52-week low$0.0833
Median price$0.0858
Average price$0.0852
Largest weekly change+9.9% (Mar 19, 2025)
Weeks tracked86
Tracking sinceJan 1, 2025

Price History

1W

-1.0%

1M

-1.0%

3M

-5.5%

6M

+0.8%

1Y

-3.2%

3Y

N/A

5Y

N/A

All

+9.3%

Generic Alternatives

The matcher finds 14 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of CHLORTHALIDONE 25 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for CHLORTHALIDONE 25 MG TABLET, manufactured by Rising Pharma Holdings Inc., is $0.0840 per EA (NDC 64980059910), effective Aug 19, 2026.

How has the price of CHLORTHALIDONE 25 MG TABLET changed over time?

Over the history we have for it, the NADAC for CHLORTHALIDONE 25 MG TABLET has risen 9.3%. It has been tracked across 86 weekly CMS publications since Jan 1, 2025.

What are the highest and lowest recorded NADAC prices for CHLORTHALIDONE 25 MG TABLET?

Since Jan 1, 2025, the NADAC for CHLORTHALIDONE 25 MG TABLET has ranged from a low of $0.0745 (Jan 22, 2025) to a high of $0.0901 (May 13, 2026), with a median of $0.0858 per EA.

Are there cheaper alternatives to CHLORTHALIDONE 25 MG TABLET?

14 manufacturers publish a NADAC-priced product with the same active ingredient and strength as CHLORTHALIDONE 25 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures CHLORTHALIDONE 25 MG TABLET?

CHLORTHALIDONE 25 MG TABLET (NDC 64980059910) is labeled by Rising Pharma Holdings Inc., and CMS classifies it as a generic product.