Product Information
CHLORTHALIDONE 25 MG TABLET is a generic product labeled by Rising Pharma Holdings Inc., priced at $0.0743 per EA under NDC 64980059910. Its NADAC has been published 92 times since Jan 1, 2025.
FDA first approved this application on Feb 9, 2022. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25 mg/1
Manufacturer
Rising Pharma Holdings Inc.NDC
64980059910
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
CHLORTHALIDONEApproval Type
Generic (ANDA)
FDA Application
ANDA211320FDA Approved
2/9/2022
TE Code
AB
On Market Since
10/23/2024
Pharmacological Classes
Price Statistics
The NADAC for CHLORTHALIDONE 25 MG TABLET has been published 92 times since Jan 1, 2025, and over the history we have for it it has declined 3.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0743 per EA |
|---|---|
| All-time high | $0.0901 (May 13, 2026) |
| All-time low | $0.0743 (Sep 23, 2026) |
| 52-week high | $0.0901 |
| 52-week low | $0.0743 |
| Median price | $0.0855 |
| Average price | $0.0849 |
| Largest weekly change | -11.5% (Sep 23, 2026) |
| Weeks tracked | 92 |
| Tracking since | Jan 1, 2025 |
Generic Alternatives
The matcher finds 14 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Rising Pharma Holdings Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Chlorthalidone market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Thiazide-like Diuretic class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of CHLORTHALIDONE 25 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for CHLORTHALIDONE 25 MG TABLET, manufactured by Rising Pharma Holdings Inc., is $0.0743 per EA (NDC 64980059910), effective Sep 30, 2026.
How has the price of CHLORTHALIDONE 25 MG TABLET changed over time?
Over the history we have for it, the NADAC for CHLORTHALIDONE 25 MG TABLET has declined 3.2%. It has been tracked across 92 weekly CMS publications since Jan 1, 2025.
What are the highest and lowest recorded NADAC prices for CHLORTHALIDONE 25 MG TABLET?
Since Jan 1, 2025, the NADAC for CHLORTHALIDONE 25 MG TABLET has ranged from a low of $0.0743 (Sep 23, 2026) to a high of $0.0901 (May 13, 2026), with a median of $0.0855 per EA.
Are there cheaper alternatives to CHLORTHALIDONE 25 MG TABLET?
14 manufacturers publish a NADAC-priced product with the same active ingredient and strength as CHLORTHALIDONE 25 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures CHLORTHALIDONE 25 MG TABLET?
CHLORTHALIDONE 25 MG TABLET (NDC 64980059910) is labeled by Rising Pharma Holdings Inc., and CMS classifies it as a generic product.