Product Information
TRAMADOL HCL 100 MG TABLET is a generic product labeled by Rising Pharma Holdings Inc., priced at $1.0261 per EA under NDC 64980066301. Its NADAC has been published 67 times since May 14, 2025.
FDA first approved this application on Jun 25, 2002. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
100 mg/1
Manufacturer
Rising Pharma Holdings Inc.NDC
64980066301
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
TRAMADOL HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA075968FDA Approved
6/25/2002
TE Code
AB
On Market Since
10/24/2024
Pharmacological Classes
Price Statistics
The NADAC for TRAMADOL HCL 100 MG TABLET has been published 67 times since May 14, 2025, and over the history we have for it it has declined 18.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.0261 per EA |
|---|---|
| All-time high | $1.2627 (May 14, 2025) |
| All-time low | $0.9096 (Dec 17, 2025) |
| 52-week high | $1.1153 |
| 52-week low | $0.9096 |
| Median price | $1.0336 |
| Average price | $1.0495 |
| Largest weekly change | -7.9% (Oct 22, 2025) |
| Weeks tracked | 67 |
| Tracking since | May 14, 2025 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of TRAMADOL HCL 100 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for TRAMADOL HCL 100 MG TABLET, manufactured by Rising Pharma Holdings Inc., is $1.0261 per EA (NDC 64980066301), effective Aug 19, 2026.
How has the price of TRAMADOL HCL 100 MG TABLET changed over time?
Over the history we have for it, the NADAC for TRAMADOL HCL 100 MG TABLET has declined 18.7%. It has been tracked across 67 weekly CMS publications since May 14, 2025.
What are the highest and lowest recorded NADAC prices for TRAMADOL HCL 100 MG TABLET?
Since May 14, 2025, the NADAC for TRAMADOL HCL 100 MG TABLET has ranged from a low of $0.9096 (Dec 17, 2025) to a high of $1.2627 (May 14, 2025), with a median of $1.0336 per EA.
Are there cheaper alternatives to TRAMADOL HCL 100 MG TABLET?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as TRAMADOL HCL 100 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures TRAMADOL HCL 100 MG TABLET?
TRAMADOL HCL 100 MG TABLET (NDC 64980066301) is labeled by Rising Pharma Holdings Inc., and CMS classifies it as a generic product.