Product Information
TRAMADOL HCL 100 MG TABLET is a generic product labeled by Advagen Pharma Ltd., priced at $1.0826 per EA under NDC 72888000801. Its NADAC has been published 200 times since Dec 7, 2022.
FDA first approved this application on Jun 28, 2019. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
100 mg/1
Manufacturer
Advagen Pharma Ltd.NDC
72888000801
Classification
Generic
Dosage Form
TABLET, COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
TRAMADOL HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA208708FDA Approved
6/28/2019
TE Code
AB
On Market Since
2/24/2020
Pharmacological Classes
Price Statistics
The NADAC for TRAMADOL HCL 100 MG TABLET has been published 200 times since Dec 7, 2022, and over the history we have for it it has declined 21.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.0826 per EA |
|---|---|
| All-time high | $1.3836 (Dec 14, 2022) |
| All-time low | $0.9096 (Dec 17, 2025) |
| 52-week high | $1.0826 |
| 52-week low | $0.9096 |
| Median price | $1.2436 |
| Average price | $1.1891 |
| Largest weekly change | +10.5% (Dec 20, 2023) |
| Weeks tracked | 200 |
| Tracking since | Dec 7, 2022 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Advagen Pharma Ltd. manufacturer profile
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Drug market
Tramadol Hydrochloride market comparison
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Therapeutic class
Opioid Agonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of TRAMADOL HCL 100 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for TRAMADOL HCL 100 MG TABLET, manufactured by Advagen Pharma Ltd., is $1.0826 per EA (NDC 72888000801), effective Sep 30, 2026.
How has the price of TRAMADOL HCL 100 MG TABLET changed over time?
Over the history we have for it, the NADAC for TRAMADOL HCL 100 MG TABLET has declined 21.8%. It has been tracked across 200 weekly CMS publications since Dec 7, 2022.
What are the highest and lowest recorded NADAC prices for TRAMADOL HCL 100 MG TABLET?
Since Dec 7, 2022, the NADAC for TRAMADOL HCL 100 MG TABLET has ranged from a low of $0.9096 (Dec 17, 2025) to a high of $1.3836 (Dec 14, 2022), with a median of $1.2436 per EA.
Are there cheaper alternatives to TRAMADOL HCL 100 MG TABLET?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as TRAMADOL HCL 100 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures TRAMADOL HCL 100 MG TABLET?
TRAMADOL HCL 100 MG TABLET (NDC 72888000801) is labeled by Advagen Pharma Ltd., and CMS classifies it as a generic product.