Product Information

LYLLANA 0.075 MG PATCH is a generic product labeled by Amneal Pharmaceuticals LLC, priced at $7.3032 per EA under NDC 65162015008. Its NADAC has been published 282 times since Feb 3, 2021.

LYLLANA 0.075 MG PATCH

Estradiol
$7.3032per EA

Strength

.075 mg/d

NDC

65162015008

Classification

Generic

Dosage Form

PATCH, EXTENDED RELEASE

Route

TRANSDERMAL

Last Updated

6/17/2026

Active Ingredients

ESTRADIOL

Approval Type

Generic (ANDA)

FDA Application

ANDA211396

On Market Since

9/30/2020

Pharmacological Classes

Estradiol Congeners
Estrogen Receptor Agonists
Estrogen

Price Statistics

The NADAC for LYLLANA 0.075 MG PATCH has been published 282 times since Feb 3, 2021, and over the history we have for it it has declined 12.2%. The table below summarizes its recorded NADAC range and movement.

Current price$7.3032 per EA
All-time high$9.3768 (Mar 10, 2021)
All-time low$5.2541 (May 22, 2024)
52-week high$7.3032
52-week low$6.8560
Median price$6.9209
Average price$6.9831
Largest weekly change+31.0% (Jun 19, 2024)
Weeks tracked282
Tracking sinceFeb 3, 2021

Price History

1W

0.0%

1M

+6.1%

3M

+4.9%

6M

+2.7%

1Y

+5.8%

3Y

+6.3%

5Y

-3.6%

All

-12.2%

Generic Alternatives

The matcher finds 4 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 4 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of LYLLANA 0.075 MG PATCH?

The current National Average Drug Acquisition Cost (NADAC) for LYLLANA 0.075 MG PATCH, manufactured by Amneal Pharmaceuticals LLC, is $7.3032 per EA (NDC 65162015008), effective Jun 24, 2026.

How has the price of LYLLANA 0.075 MG PATCH changed over time?

Over the history we have for it, the NADAC for LYLLANA 0.075 MG PATCH has declined 12.2%. It has been tracked across 282 weekly CMS publications since Feb 3, 2021.

What are the highest and lowest recorded NADAC prices for LYLLANA 0.075 MG PATCH?

Since Feb 3, 2021, the NADAC for LYLLANA 0.075 MG PATCH has ranged from a low of $5.2541 (May 22, 2024) to a high of $9.3768 (Mar 10, 2021), with a median of $6.9209 per EA.

Are there cheaper alternatives to LYLLANA 0.075 MG PATCH?

4 NADAC-published products share the same active ingredient, strength, and dosage form as LYLLANA 0.075 MG PATCH, but none are currently priced below it.

Who manufactures LYLLANA 0.075 MG PATCH?

LYLLANA 0.075 MG PATCH (NDC 65162015008) is labeled by Amneal Pharmaceuticals LLC, and CMS classifies it as a generic product.