Product Information
LYLLANA 0.075 MG PATCH is a generic product labeled by Amneal Pharmaceuticals LLC, priced at $8.0918 per EA under NDC 65162015008. Its NADAC has been published 290 times since Feb 3, 2021.
FDA first approved this application on Sep 28, 2020. Its Orange Book therapeutic-equivalence code is AB3 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.075 mg/d
Manufacturer
Amneal Pharmaceuticals LLCNDC
65162015008
Classification
Generic
Dosage Form
PATCH, EXTENDED RELEASE
Route
TRANSDERMAL
Effective Date
8/19/2026
Active Ingredients
ESTRADIOLApproval Type
Generic (ANDA)
FDA Application
ANDA211396FDA Approved
9/28/2020
TE Code
AB3
On Market Since
9/30/2020
Pharmacological Classes
Price Statistics
The NADAC for LYLLANA 0.075 MG PATCH has been published 290 times since Feb 3, 2021, and over the history we have for it it has declined 2.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $8.0918 per EA |
|---|---|
| All-time high | $9.3768 (Mar 10, 2021) |
| All-time low | $5.2541 (May 22, 2024) |
| 52-week high | $8.0918 |
| 52-week low | $6.8560 |
| Median price | $6.9242 |
| Average price | $7.0000 |
| Largest weekly change | +31.0% (Jun 19, 2024) |
| Weeks tracked | 290 |
| Tracking since | Feb 3, 2021 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of LYLLANA 0.075 MG PATCH?
The current National Average Drug Acquisition Cost (NADAC) for LYLLANA 0.075 MG PATCH, manufactured by Amneal Pharmaceuticals LLC, is $8.0918 per EA (NDC 65162015008), effective Aug 19, 2026.
How has the price of LYLLANA 0.075 MG PATCH changed over time?
Over the history we have for it, the NADAC for LYLLANA 0.075 MG PATCH has declined 2.7%. It has been tracked across 290 weekly CMS publications since Feb 3, 2021.
What are the highest and lowest recorded NADAC prices for LYLLANA 0.075 MG PATCH?
Since Feb 3, 2021, the NADAC for LYLLANA 0.075 MG PATCH has ranged from a low of $5.2541 (May 22, 2024) to a high of $9.3768 (Mar 10, 2021), with a median of $6.9242 per EA.
Are there cheaper alternatives to LYLLANA 0.075 MG PATCH?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as LYLLANA 0.075 MG PATCH in a comparable dosage form, but none are currently priced below it.
Who manufactures LYLLANA 0.075 MG PATCH?
LYLLANA 0.075 MG PATCH (NDC 65162015008) is labeled by Amneal Pharmaceuticals LLC, and CMS classifies it as a generic product.