Product Information
CLIMARA 0.075 MG/DAY PATCH is a brand product labeled by Bayer HealthCare Pharmaceuticals Inc., priced at $18.2956 per EA under NDC 50419045304. Its NADAC has been published 314 times since Nov 28, 2013.
The High Outlier badge above means this manufacturer's average price in the Estradiol market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
.075 mg/d
Manufacturer
Bayer HealthCare Pharmaceuticals Inc.NDC
50419045304
Classification
Brand
Dosage Form
PATCH
Route
TRANSDERMAL
Last Updated
6/17/2026
Active Ingredients
ESTRADIOLApproval Type
New Drug (NDA)
FDA Application
NDA020375On Market Since
3/23/1998
Pharmacological Classes
Price Statistics
The NADAC for CLIMARA 0.075 MG/DAY PATCH has been published 314 times since Nov 28, 2013, and over the history we have for it it has declined 21.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $18.2956 per EA |
|---|---|
| All-time high | $28.0547 (Oct 12, 2016) |
| All-time low | $18.2725 (Mar 18, 2026) |
| 52-week high | $18.3039 |
| 52-week low | $18.2725 |
| Median price | $25.4275 |
| Average price | $23.4087 |
| Largest weekly change | -32.8% (Jun 19, 2024) |
| Weeks tracked | 314 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 3 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 3 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 60% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of CLIMARA 0.075 MG/DAY PATCH?
The current National Average Drug Acquisition Cost (NADAC) for CLIMARA 0.075 MG/DAY PATCH, manufactured by Bayer HealthCare Pharmaceuticals Inc., is $18.2956 per EA (NDC 50419045304), effective Jun 24, 2026.
How has the price of CLIMARA 0.075 MG/DAY PATCH changed over time?
Over the history we have for it, the NADAC for CLIMARA 0.075 MG/DAY PATCH has declined 21.2%. It has been tracked across 314 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for CLIMARA 0.075 MG/DAY PATCH?
Since Nov 28, 2013, the NADAC for CLIMARA 0.075 MG/DAY PATCH has ranged from a low of $18.2725 (Mar 18, 2026) to a high of $28.0547 (Oct 12, 2016), with a median of $25.4275 per EA.
Are there cheaper alternatives to CLIMARA 0.075 MG/DAY PATCH?
Yes. 3 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, LYLLANA 0.075 MG PATCH, is $7.3032 per EA — about 60% below CLIMARA 0.075 MG/DAY PATCH.
Who manufactures CLIMARA 0.075 MG/DAY PATCH?
CLIMARA 0.075 MG/DAY PATCH (NDC 50419045304) is labeled by Bayer HealthCare Pharmaceuticals Inc., and CMS classifies it as a brand product.
Related Drugs
Same classification