Historical record - last NADAC effective date: 11/23/2022
Product Information
NAPROXEN 375 MG TABLET is a generic product labeled by Amneal Pharmaceuticals LLC, priced at $0.0732 per EA under NDC 65162018911. Its NADAC has been published 400 times since Apr 1, 2015.
FDA first approved this application on Dec 18, 2001. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
375 mg/1
Manufacturer
Amneal Pharmaceuticals LLCNDC
65162018911
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
11/23/2022
Active Ingredients
NAPROXENApproval Type
Generic (ANDA)
FDA Application
ANDA075927FDA Approved
12/18/2001
TE Code
AB
On Market Since
2/18/2010
Pharmacological Classes
Price Statistics
The NADAC for NAPROXEN 375 MG TABLET has been published 400 times since Apr 1, 2015, and over the history we have for it it has risen 68.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0732 per EA |
|---|---|
| All-time high | $0.0808 (Jun 16, 2021) |
| All-time low | $0.0435 (Apr 1, 2015) |
| Median price | $0.0658 |
| Average price | $0.0669 |
| Largest weekly change | +36.8% (Apr 22, 2015) |
| Weeks tracked | 400 |
| Tracking since | Apr 1, 2015 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
N/A
3Y
N/A
5Y
-4.2%
All
+68.3%
Last surveyed Dec 14, 2022 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 10 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 23% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of NAPROXEN 375 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for NAPROXEN 375 MG TABLET, manufactured by Amneal Pharmaceuticals LLC, is $0.0732 per EA (NDC 65162018911), effective Dec 14, 2022.
How has the price of NAPROXEN 375 MG TABLET changed over time?
Over the history we have for it, the NADAC for NAPROXEN 375 MG TABLET has risen 68.3%. It has been tracked across 400 weekly CMS publications since Apr 1, 2015.
What are the highest and lowest recorded NADAC prices for NAPROXEN 375 MG TABLET?
Since Apr 1, 2015, the NADAC for NAPROXEN 375 MG TABLET has ranged from a low of $0.0435 (Apr 1, 2015) to a high of $0.0808 (Jun 16, 2021), with a median of $0.0658 per EA.
Are there cheaper alternatives to NAPROXEN 375 MG TABLET?
Yes. 10 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, NAPROXEN 375 MG TABLET, is $0.0561 per EA — about 23% below NAPROXEN 375 MG TABLET.
Who manufactures NAPROXEN 375 MG TABLET?
NAPROXEN 375 MG TABLET (NDC 65162018911) is labeled by Amneal Pharmaceuticals LLC, and CMS classifies it as a generic product.