Product Information
NAPROXEN 375 MG TABLET is a generic product labeled by Amneal Pharmaceuticals LLC, priced at $0.0573 per EA under NDC 65162018910. Its NADAC has been published 584 times since Apr 1, 2015.
Strength
375 mg/1
Manufacturer
Amneal Pharmaceuticals LLCNDC
65162018910
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
NAPROXENApproval Type
Generic (ANDA)
FDA Application
ANDA075927On Market Since
2/18/2010
Pharmacological Classes
Price Statistics
The NADAC for NAPROXEN 375 MG TABLET has been published 584 times since Apr 1, 2015, and over the history we have for it it has risen 31.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0573 per EA |
|---|---|
| All-time high | $0.0808 (Jun 16, 2021) |
| All-time low | $0.0435 (Apr 1, 2015) |
| 52-week high | $0.0620 |
| 52-week low | $0.0573 |
| Median price | $0.0634 |
| Average price | $0.0653 |
| Largest weekly change | +36.8% (Apr 22, 2015) |
| Weeks tracked | 584 |
| Tracking since | Apr 1, 2015 |
Generic Alternatives
The matcher finds 10 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 10 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of NAPROXEN 375 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for NAPROXEN 375 MG TABLET, manufactured by Amneal Pharmaceuticals LLC, is $0.0573 per EA (NDC 65162018910), effective Jun 24, 2026.
How has the price of NAPROXEN 375 MG TABLET changed over time?
Over the history we have for it, the NADAC for NAPROXEN 375 MG TABLET has risen 31.6%. It has been tracked across 584 weekly CMS publications since Apr 1, 2015.
What are the highest and lowest recorded NADAC prices for NAPROXEN 375 MG TABLET?
Since Apr 1, 2015, the NADAC for NAPROXEN 375 MG TABLET has ranged from a low of $0.0435 (Apr 1, 2015) to a high of $0.0808 (Jun 16, 2021), with a median of $0.0634 per EA.
Are there cheaper alternatives to NAPROXEN 375 MG TABLET?
10 NADAC-published products share the same active ingredient, strength, and dosage form as NAPROXEN 375 MG TABLET, but none are currently priced below it.
Who manufactures NAPROXEN 375 MG TABLET?
NAPROXEN 375 MG TABLET (NDC 65162018910) is labeled by Amneal Pharmaceuticals LLC, and CMS classifies it as a generic product.
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