Product Information

NAPROXEN 375 MG TABLET is a generic product labeled by ScieGen Pharmaceuticals, Inc., priced at $0.0561 per EA under NDC 50228043501. Its NADAC has been published 319 times since Jul 15, 2020.

FDA first approved this application on Feb 21, 2020. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

NAPROXEN 375 MG TABLET

Naproxen
$0.0561per EA

Strength

375 mg/1

NDC

50228043501

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

NAPROXEN

Approval Type

Generic (ANDA)

FDA Application

ANDA212517

FDA Approved

2/21/2020

TE Code

AB

On Market Since

3/1/2020

Pharmacological Classes

Anti-Inflammatory Agents
Non-Steroidal
Cyclooxygenase Inhibitors
Nonsteroidal Anti-inflammatory Drug

Price Statistics

The NADAC for NAPROXEN 375 MG TABLET has been published 319 times since Jul 15, 2020, and over the history we have for it it has declined 24.8%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0561 per EA
All-time high$0.0808 (Jun 16, 2021)
All-time low$0.0474 (Apr 17, 2024)
52-week high$0.0607
52-week low$0.0561
Median price$0.0677
Average price$0.0668
Largest weekly change-28.8% (Apr 17, 2024)
Weeks tracked319
Tracking sinceJul 15, 2020

Price History

1W

-1.0%

1M

-1.0%

3M

-4.7%

6M

-4.1%

1Y

-7.5%

3Y

-12.9%

5Y

-26.5%

All

-24.8%

Generic Alternatives

The matcher finds 10 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of NAPROXEN 375 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for NAPROXEN 375 MG TABLET, manufactured by ScieGen Pharmaceuticals, Inc., is $0.0561 per EA (NDC 50228043501), effective Aug 19, 2026.

How has the price of NAPROXEN 375 MG TABLET changed over time?

Over the history we have for it, the NADAC for NAPROXEN 375 MG TABLET has declined 24.8%. It has been tracked across 319 weekly CMS publications since Jul 15, 2020.

What are the highest and lowest recorded NADAC prices for NAPROXEN 375 MG TABLET?

Since Jul 15, 2020, the NADAC for NAPROXEN 375 MG TABLET has ranged from a low of $0.0474 (Apr 17, 2024) to a high of $0.0808 (Jun 16, 2021), with a median of $0.0677 per EA.

Are there cheaper alternatives to NAPROXEN 375 MG TABLET?

10 manufacturers publish a NADAC-priced product with the same active ingredient and strength as NAPROXEN 375 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures NAPROXEN 375 MG TABLET?

NAPROXEN 375 MG TABLET (NDC 50228043501) is labeled by ScieGen Pharmaceuticals, Inc., and CMS classifies it as a generic product.