Product Information
YUVAFEM 10 MCG VAGINAL INSERT is a generic product labeled by Amneal Pharmaceuticals LLC, priced at $5.6451 per EA under NDC 65162022623. Its NADAC has been published 492 times since Mar 22, 2017.
FDA first approved this application on May 29, 2015. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
10 ug/1
Manufacturer
Amneal Pharmaceuticals LLCNDC
65162022623
Classification
Generic
Dosage Form
TABLET
Route
VAGINAL
Effective Date
8/19/2026
Active Ingredients
ESTRADIOLApproval Type
Generic (ANDA)
FDA Application
ANDA205256FDA Approved
5/29/2015
TE Code
AB
On Market Since
10/17/2016
Pharmacological Classes
Price Statistics
The NADAC for YUVAFEM 10 MCG VAGINAL INSERT has been published 492 times since Mar 22, 2017, and over the history we have for it it has declined 67.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $5.6451 per EA |
|---|---|
| All-time high | $17.2273 (Apr 12, 2017) |
| All-time low | $5.0022 (Nov 20, 2024) |
| 52-week high | $7.0095 |
| 52-week low | $5.6451 |
| Median price | $9.7875 |
| Average price | $10.2035 |
| Largest weekly change | -28.9% (Nov 20, 2024) |
| Weeks tracked | 492 |
| Tracking since | Mar 22, 2017 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of YUVAFEM 10 MCG VAGINAL INSERT?
The current National Average Drug Acquisition Cost (NADAC) for YUVAFEM 10 MCG VAGINAL INSERT, manufactured by Amneal Pharmaceuticals LLC, is $5.6451 per EA (NDC 65162022623), effective Aug 19, 2026.
How has the price of YUVAFEM 10 MCG VAGINAL INSERT changed over time?
Over the history we have for it, the NADAC for YUVAFEM 10 MCG VAGINAL INSERT has declined 67.2%. It has been tracked across 492 weekly CMS publications since Mar 22, 2017.
What are the highest and lowest recorded NADAC prices for YUVAFEM 10 MCG VAGINAL INSERT?
Since Mar 22, 2017, the NADAC for YUVAFEM 10 MCG VAGINAL INSERT has ranged from a low of $5.0022 (Nov 20, 2024) to a high of $17.2273 (Apr 12, 2017), with a median of $9.7875 per EA.
Are there cheaper alternatives to YUVAFEM 10 MCG VAGINAL INSERT?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as YUVAFEM 10 MCG VAGINAL INSERT in a comparable dosage form, but none are currently priced below it.
Who manufactures YUVAFEM 10 MCG VAGINAL INSERT?
YUVAFEM 10 MCG VAGINAL INSERT (NDC 65162022623) is labeled by Amneal Pharmaceuticals LLC, and CMS classifies it as a generic product.