Product Information

CHLORTHALIDONE 50 MG TABLET is a generic product labeled by Amneal Pharmaceuticals LLC, priced at $0.1210 per EA under NDC 65162025009. Its NADAC has been published 364 times since Sep 4, 2019.

FDA first approved this application on Jul 1, 2019. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

CHLORTHALIDONE 50 MG TABLET

Chlorthalidone
$0.1210per EA

Strength

50 mg/1

NDC

65162025009

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

CHLORTHALIDONE

Approval Type

Generic (ANDA)

FDA Application

ANDA207204

FDA Approved

7/1/2019

TE Code

AB

On Market Since

7/1/2019

Pharmacological Classes

Increased Diuresis
Thiazide-like Diuretic

Price Statistics

The NADAC for CHLORTHALIDONE 50 MG TABLET has been published 364 times since Sep 4, 2019, and over the history we have for it it has declined 84.0%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1210 per EA
All-time high$0.7582 (Sep 11, 2019)
All-time low$0.0987 (May 22, 2024)
52-week high$0.1453
52-week low$0.1210
Median price$0.1706
Average price$0.2549
Largest weekly change+48.7% (Mar 23, 2022)
Weeks tracked364
Tracking sinceSep 4, 2019

Price History

1W

-2.7%

1M

-2.7%

3M

-9.7%

6M

-9.6%

1Y

-8.9%

3Y

-6.9%

5Y

-60.4%

All

-84.0%

Generic Alternatives

The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of CHLORTHALIDONE 50 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for CHLORTHALIDONE 50 MG TABLET, manufactured by Amneal Pharmaceuticals LLC, is $0.1210 per EA (NDC 65162025009), effective Aug 19, 2026.

How has the price of CHLORTHALIDONE 50 MG TABLET changed over time?

Over the history we have for it, the NADAC for CHLORTHALIDONE 50 MG TABLET has declined 84.0%. It has been tracked across 364 weekly CMS publications since Sep 4, 2019.

What are the highest and lowest recorded NADAC prices for CHLORTHALIDONE 50 MG TABLET?

Since Sep 4, 2019, the NADAC for CHLORTHALIDONE 50 MG TABLET has ranged from a low of $0.0987 (May 22, 2024) to a high of $0.7582 (Sep 11, 2019), with a median of $0.1706 per EA.

Are there cheaper alternatives to CHLORTHALIDONE 50 MG TABLET?

11 manufacturers publish a NADAC-priced product with the same active ingredient and strength as CHLORTHALIDONE 50 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures CHLORTHALIDONE 50 MG TABLET?

CHLORTHALIDONE 50 MG TABLET (NDC 65162025009) is labeled by Amneal Pharmaceuticals LLC, and CMS classifies it as a generic product.