Product Information

CHLORTHALIDONE 50 MG TABLET is a generic product labeled by Rising Pharma Holdings Inc., priced at $0.1210 per EA under NDC 64980060001. Its NADAC has been published 80 times since Feb 12, 2025.

FDA first approved this application on Feb 9, 2022. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

CHLORTHALIDONE 50 MG TABLET

Chlorthalidone
$0.1210per EA

Strength

50 mg/1

NDC

64980060001

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

CHLORTHALIDONE

Approval Type

Generic (ANDA)

FDA Application

ANDA211320

FDA Approved

2/9/2022

TE Code

AB

On Market Since

10/23/2024

Pharmacological Classes

Increased Diuresis
Thiazide-like Diuretic

Price Statistics

The NADAC for CHLORTHALIDONE 50 MG TABLET has been published 80 times since Feb 12, 2025, and over the history we have for it it has risen 7.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1210 per EA
All-time high$0.1453 (Jan 14, 2026)
All-time low$0.1124 (Feb 12, 2025)
52-week high$0.1453
52-week low$0.1210
Median price$0.1327
Average price$0.1319
Largest weekly change+7.8% (Mar 19, 2025)
Weeks tracked80
Tracking sinceFeb 12, 2025

Price History

1W

-2.7%

1M

-2.7%

3M

-9.7%

6M

-9.6%

1Y

-8.9%

3Y

N/A

5Y

N/A

All

+7.6%

Generic Alternatives

The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of CHLORTHALIDONE 50 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for CHLORTHALIDONE 50 MG TABLET, manufactured by Rising Pharma Holdings Inc., is $0.1210 per EA (NDC 64980060001), effective Aug 19, 2026.

How has the price of CHLORTHALIDONE 50 MG TABLET changed over time?

Over the history we have for it, the NADAC for CHLORTHALIDONE 50 MG TABLET has risen 7.6%. It has been tracked across 80 weekly CMS publications since Feb 12, 2025.

What are the highest and lowest recorded NADAC prices for CHLORTHALIDONE 50 MG TABLET?

Since Feb 12, 2025, the NADAC for CHLORTHALIDONE 50 MG TABLET has ranged from a low of $0.1124 (Feb 12, 2025) to a high of $0.1453 (Jan 14, 2026), with a median of $0.1327 per EA.

Are there cheaper alternatives to CHLORTHALIDONE 50 MG TABLET?

11 manufacturers publish a NADAC-priced product with the same active ingredient and strength as CHLORTHALIDONE 50 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures CHLORTHALIDONE 50 MG TABLET?

CHLORTHALIDONE 50 MG TABLET (NDC 64980060001) is labeled by Rising Pharma Holdings Inc., and CMS classifies it as a generic product.