Product Information
CHLORTHALIDONE 50 MG TABLET is a generic product labeled by Rising Pharma Holdings Inc., priced at $0.1217 per EA under NDC 64980060001. Its NADAC has been published 86 times since Feb 12, 2025.
FDA first approved this application on Feb 9, 2022. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/1
Manufacturer
Rising Pharma Holdings Inc.NDC
64980060001
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
CHLORTHALIDONEApproval Type
Generic (ANDA)
FDA Application
ANDA211320FDA Approved
2/9/2022
TE Code
AB
On Market Since
10/23/2024
Pharmacological Classes
Price Statistics
The NADAC for CHLORTHALIDONE 50 MG TABLET has been published 86 times since Feb 12, 2025, and over the history we have for it it has risen 8.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1217 per EA |
|---|---|
| All-time high | $0.1453 (Jan 14, 2026) |
| All-time low | $0.1124 (Feb 12, 2025) |
| 52-week high | $0.1453 |
| 52-week low | $0.1210 |
| Median price | $0.1319 |
| Average price | $0.1311 |
| Largest weekly change | +7.8% (Mar 19, 2025) |
| Weeks tracked | 86 |
| Tracking since | Feb 12, 2025 |
Generic Alternatives
The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Rising Pharma Holdings Inc. manufacturer profile
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Drug market
Chlorthalidone market comparison
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Therapeutic class
Thiazide-like Diuretic class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of CHLORTHALIDONE 50 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for CHLORTHALIDONE 50 MG TABLET, manufactured by Rising Pharma Holdings Inc., is $0.1217 per EA (NDC 64980060001), effective Sep 30, 2026.
How has the price of CHLORTHALIDONE 50 MG TABLET changed over time?
Over the history we have for it, the NADAC for CHLORTHALIDONE 50 MG TABLET has risen 8.3%. It has been tracked across 86 weekly CMS publications since Feb 12, 2025.
What are the highest and lowest recorded NADAC prices for CHLORTHALIDONE 50 MG TABLET?
Since Feb 12, 2025, the NADAC for CHLORTHALIDONE 50 MG TABLET has ranged from a low of $0.1124 (Feb 12, 2025) to a high of $0.1453 (Jan 14, 2026), with a median of $0.1319 per EA.
Are there cheaper alternatives to CHLORTHALIDONE 50 MG TABLET?
11 manufacturers publish a NADAC-priced product with the same active ingredient and strength as CHLORTHALIDONE 50 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures CHLORTHALIDONE 50 MG TABLET?
CHLORTHALIDONE 50 MG TABLET (NDC 64980060001) is labeled by Rising Pharma Holdings Inc., and CMS classifies it as a generic product.