Product Information
TRAMADOL HCL 50 MG TABLET is a generic product labeled by Amneal Pharmaceuticals LLC, priced at $0.0245 per EA under NDC 65162062711. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Jun 20, 2002. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/1
Manufacturer
Amneal Pharmaceuticals LLCNDC
65162062711
Classification
Generic
Dosage Form
TABLET, COATED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
TRAMADOL HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA076003FDA Approved
6/20/2002
TE Code
AB
On Market Since
11/15/2010
Pharmacological Classes
Price Statistics
The NADAC for TRAMADOL HCL 50 MG TABLET has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 30.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0245 per EA |
|---|---|
| All-time high | $0.0355 (Apr 10, 2024) |
| All-time low | $0.0171 (Dec 20, 2017) |
| 52-week high | $0.0254 |
| 52-week low | $0.0235 |
| Median price | $0.0237 |
| Average price | $0.0236 |
| Largest weekly change | -31.3% (Nov 20, 2024) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 9 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 3% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of TRAMADOL HCL 50 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for TRAMADOL HCL 50 MG TABLET, manufactured by Amneal Pharmaceuticals LLC, is $0.0245 per EA (NDC 65162062711), effective Aug 19, 2026.
How has the price of TRAMADOL HCL 50 MG TABLET changed over time?
Over the history we have for it, the NADAC for TRAMADOL HCL 50 MG TABLET has risen 30.3%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for TRAMADOL HCL 50 MG TABLET?
Since Nov 28, 2013, the NADAC for TRAMADOL HCL 50 MG TABLET has ranged from a low of $0.0171 (Dec 20, 2017) to a high of $0.0355 (Apr 10, 2024), with a median of $0.0237 per EA.
Are there cheaper alternatives to TRAMADOL HCL 50 MG TABLET?
Yes. 9 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, TRAMADOL HCL 50 MG TABLET, is $0.0239 per EA — about 3% below TRAMADOL HCL 50 MG TABLET.
Who manufactures TRAMADOL HCL 50 MG TABLET?
TRAMADOL HCL 50 MG TABLET (NDC 65162062711) is labeled by Amneal Pharmaceuticals LLC, and CMS classifies it as a generic product.