Product Information
VIVELLE-DOT 0.05 MG PATCH is a brand product labeled by Sandoz Inc., priced at $18.4026 per EA under NDC 66758014783. Its NADAC has been published 53 times since Aug 20, 2025.
FDA first approved this application on Jan 8, 1999. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.05 mg/d
Manufacturer
Sandoz Inc.NDC
66758014783
Classification
Brand
Dosage Form
PATCH, EXTENDED RELEASE
Route
TRANSDERMAL
Effective Date
8/19/2026
Active Ingredients
ESTRADIOLApproval Type
New Drug (NDA)
FDA Application
NDA020538FDA Approved
1/8/1999
TE Code
AB1
On Market Since
1/8/1999
Pharmacological Classes
Price Statistics
The NADAC for VIVELLE-DOT 0.05 MG PATCH has been published 53 times since Aug 20, 2025, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $18.4026 per EA |
|---|---|
| All-time high | $18.4677 (Sep 10, 2025) |
| All-time low | $18.4026 (Aug 19, 2026) |
| 52-week high | $18.4677 |
| 52-week low | $18.4026 |
| Median price | $18.4271 |
| Average price | $18.4307 |
| Largest weekly change | -0.1% (Sep 17, 2025) |
| Weeks tracked | 53 |
| Tracking since | Aug 20, 2025 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 55% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of VIVELLE-DOT 0.05 MG PATCH?
The current National Average Drug Acquisition Cost (NADAC) for VIVELLE-DOT 0.05 MG PATCH, manufactured by Sandoz Inc., is $18.4026 per EA (NDC 66758014783), effective Aug 19, 2026.
How has the price of VIVELLE-DOT 0.05 MG PATCH changed over time?
Over the history we have for it, the NADAC for VIVELLE-DOT 0.05 MG PATCH has held within roughly two percent of its current level. It has been tracked across 53 weekly CMS publications since Aug 20, 2025.
What are the highest and lowest recorded NADAC prices for VIVELLE-DOT 0.05 MG PATCH?
Since Aug 20, 2025, the NADAC for VIVELLE-DOT 0.05 MG PATCH has ranged from a low of $18.4026 (Aug 19, 2026) to a high of $18.4677 (Sep 10, 2025), with a median of $18.4271 per EA.
Are there cheaper alternatives to VIVELLE-DOT 0.05 MG PATCH?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ESTRADIOL 0.05 MG PATCH (2/WK), is $8.2223 per EA — about 55% below VIVELLE-DOT 0.05 MG PATCH.
Who manufactures VIVELLE-DOT 0.05 MG PATCH?
VIVELLE-DOT 0.05 MG PATCH (NDC 66758014783) is labeled by Sandoz Inc., and CMS classifies it as a brand product.