Product Information
VIVELLE-DOT 0.1 MG PATCH is a brand product labeled by Sandoz Inc., priced at $18.3986 per EA under NDC 66758014983. Its NADAC has been published 102 times since Oct 23, 2024.
FDA first approved this application on Jan 8, 1999. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.1 mg/d
Manufacturer
Sandoz Inc.NDC
66758014983
Classification
Brand
Dosage Form
PATCH, EXTENDED RELEASE
Route
TRANSDERMAL
Effective Date
9/23/2026
Active Ingredients
ESTRADIOLApproval Type
New Drug (NDA)
FDA Application
NDA020538FDA Approved
1/8/1999
TE Code
AB1
On Market Since
1/8/1999
Pharmacological Classes
Price Statistics
The NADAC for VIVELLE-DOT 0.1 MG PATCH has been published 102 times since Oct 23, 2024, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $18.3986 per EA |
|---|---|
| All-time high | $18.4522 (Mar 12, 2025) |
| All-time low | $18.3937 (Aug 19, 2026) |
| 52-week high | $18.4336 |
| 52-week low | $18.3937 |
| Median price | $18.4249 |
| Average price | $18.4222 |
| Largest weekly change | +0.1% (Jul 23, 2025) |
| Weeks tracked | 102 |
| Tracking since | Oct 23, 2024 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 53% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Sandoz Inc. manufacturer profile
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Therapeutic class
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Trend hub
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of VIVELLE-DOT 0.1 MG PATCH?
The current National Average Drug Acquisition Cost (NADAC) for VIVELLE-DOT 0.1 MG PATCH, manufactured by Sandoz Inc., is $18.3986 per EA (NDC 66758014983), effective Sep 30, 2026.
How has the price of VIVELLE-DOT 0.1 MG PATCH changed over time?
Over the history we have for it, the NADAC for VIVELLE-DOT 0.1 MG PATCH has held within roughly two percent of its current level. It has been tracked across 102 weekly CMS publications since Oct 23, 2024.
What are the highest and lowest recorded NADAC prices for VIVELLE-DOT 0.1 MG PATCH?
Since Oct 23, 2024, the NADAC for VIVELLE-DOT 0.1 MG PATCH has ranged from a low of $18.3937 (Aug 19, 2026) to a high of $18.4522 (Mar 12, 2025), with a median of $18.4249 per EA.
Are there cheaper alternatives to VIVELLE-DOT 0.1 MG PATCH?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ESTRADIOL 0.1 MG PATCH (2/WK), is $8.5681 per EA — about 53% below VIVELLE-DOT 0.1 MG PATCH.
Who manufactures VIVELLE-DOT 0.1 MG PATCH?
VIVELLE-DOT 0.1 MG PATCH (NDC 66758014983) is labeled by Sandoz Inc., and CMS classifies it as a brand product.