Product Information

VIVELLE-DOT 0.1 MG PATCH is a brand product labeled by Sandoz Inc., priced at $18.3937 per EA under NDC 66758014983. Its NADAC has been published 96 times since Oct 23, 2024.

FDA first approved this application on Jan 8, 1999. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

VIVELLE-DOT 0.1 MG PATCH

estradiol
$18.3937per EA

Strength

.1 mg/d

Manufacturer

Sandoz Inc.

NDC

66758014983

Classification

Brand

Dosage Form

PATCH, EXTENDED RELEASE

Route

TRANSDERMAL

Effective Date

8/19/2026

Active Ingredients

ESTRADIOL

Approval Type

New Drug (NDA)

FDA Application

NDA020538

FDA Approved

1/8/1999

TE Code

AB1

On Market Since

1/8/1999

Pharmacological Classes

Estradiol Congeners
Estrogen Receptor Agonists
Estrogen

Price Statistics

The NADAC for VIVELLE-DOT 0.1 MG PATCH has been published 96 times since Oct 23, 2024, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.

Current price$18.3937 per EA
All-time high$18.4522 (Mar 12, 2025)
All-time low$18.3937 (Aug 19, 2026)
52-week high$18.4357
52-week low$18.3937
Median price$18.4249
Average price$18.4239
Largest weekly change+0.1% (Jul 23, 2025)
Weeks tracked96
Tracking sinceOct 23, 2024

Price History

1W

-0.0%

1M

-0.1%

3M

-0.1%

6M

-0.0%

1Y

-0.3%

3Y

N/A

5Y

N/A

All

-0.2%

Generic Alternatives

The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 55% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of VIVELLE-DOT 0.1 MG PATCH?

The current National Average Drug Acquisition Cost (NADAC) for VIVELLE-DOT 0.1 MG PATCH, manufactured by Sandoz Inc., is $18.3937 per EA (NDC 66758014983), effective Aug 19, 2026.

How has the price of VIVELLE-DOT 0.1 MG PATCH changed over time?

Over the history we have for it, the NADAC for VIVELLE-DOT 0.1 MG PATCH has held within roughly two percent of its current level. It has been tracked across 96 weekly CMS publications since Oct 23, 2024.

What are the highest and lowest recorded NADAC prices for VIVELLE-DOT 0.1 MG PATCH?

Since Oct 23, 2024, the NADAC for VIVELLE-DOT 0.1 MG PATCH has ranged from a low of $18.3937 (Aug 19, 2026) to a high of $18.4522 (Mar 12, 2025), with a median of $18.4249 per EA.

Are there cheaper alternatives to VIVELLE-DOT 0.1 MG PATCH?

Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ESTRADIOL 0.1 MG PATCH (2/WK), is $8.2292 per EA — about 55% below VIVELLE-DOT 0.1 MG PATCH.

Who manufactures VIVELLE-DOT 0.1 MG PATCH?

VIVELLE-DOT 0.1 MG PATCH (NDC 66758014983) is labeled by Sandoz Inc., and CMS classifies it as a brand product.