Product Information
DIVIGEL 0.25 MG GEL PACKET is a brand product labeled by Vertical Pharmaceuticals, LLC, priced at $5.3866 per EA under NDC 68025006530. Its NADAC has been published 545 times since Jul 22, 2015.
Strength
.25 mg/.25g
Manufacturer
Vertical Pharmaceuticals, LLCNDC
68025006530
Classification
Brand
Dosage Form
GEL
Route
TOPICAL
Last Updated
6/17/2026
Active Ingredients
ESTRADIOLApproval Type
New Drug (NDA)
FDA Application
NDA022038On Market Since
10/27/2014
Pharmacological Classes
Price Statistics
The NADAC for DIVIGEL 0.25 MG GEL PACKET has been published 545 times since Jul 22, 2015, and over the history we have for it it has risen 69.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $5.3866 per EA |
|---|---|
| All-time high | $5.4088 (Oct 11, 2023) |
| All-time low | $3.1851 (Jul 22, 2015) |
| 52-week high | $5.4032 |
| 52-week low | $5.3866 |
| Median price | $4.5601 |
| Average price | $4.5463 |
| Largest weekly change | +8.1% (Feb 22, 2017) |
| Weeks tracked | 545 |
| Tracking since | Jul 22, 2015 |
Generic Alternatives
The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 74% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of DIVIGEL 0.25 MG GEL PACKET?
The current National Average Drug Acquisition Cost (NADAC) for DIVIGEL 0.25 MG GEL PACKET, manufactured by Vertical Pharmaceuticals, LLC, is $5.3866 per EA (NDC 68025006530), effective Jun 24, 2026.
How has the price of DIVIGEL 0.25 MG GEL PACKET changed over time?
Over the history we have for it, the NADAC for DIVIGEL 0.25 MG GEL PACKET has risen 69.1%. It has been tracked across 545 weekly CMS publications since Jul 22, 2015.
What are the highest and lowest recorded NADAC prices for DIVIGEL 0.25 MG GEL PACKET?
Since Jul 22, 2015, the NADAC for DIVIGEL 0.25 MG GEL PACKET has ranged from a low of $3.1851 (Jul 22, 2015) to a high of $5.4088 (Oct 11, 2023), with a median of $4.5601 per EA.
Are there cheaper alternatives to DIVIGEL 0.25 MG GEL PACKET?
Yes. 1 NADAC-published product shares the same active ingredient, strength, and dosage form. The lowest-priced option, ESTRADIOL 0.1% (0.25 MG) GEL PK, is $1.3810 per EA — about 74% below DIVIGEL 0.25 MG GEL PACKET.
Who manufactures DIVIGEL 0.25 MG GEL PACKET?
DIVIGEL 0.25 MG GEL PACKET (NDC 68025006530) is labeled by Vertical Pharmaceuticals, LLC, and CMS classifies it as a brand product.
Related Drugs
Same classification