Product Information
DIVIGEL 0.75 MG GEL PACKET is a brand product labeled by Vertical Pharmaceuticals, LLC, priced at $5.3993 per EA under NDC 68025008330. Its NADAC has been published 331 times since Apr 22, 2020.
FDA first approved this application on Jun 4, 2007. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.75 mg/.75g
Manufacturer
Vertical Pharmaceuticals, LLCNDC
68025008330
Classification
Brand
Dosage Form
GEL
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
ESTRADIOLApproval Type
New Drug (NDA)
FDA Application
NDA022038FDA Approved
6/4/2007
TE Code
AB
On Market Since
1/18/2019
Pharmacological Classes
Price Statistics
The NADAC for DIVIGEL 0.75 MG GEL PACKET has been published 331 times since Apr 22, 2020, and over the history we have for it it has risen 17.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $5.3993 per EA |
|---|---|
| All-time high | $5.4151 (Aug 14, 2024) |
| All-time low | $4.5350 (Jun 17, 2020) |
| 52-week high | $5.3993 |
| 52-week low | $5.3689 |
| Median price | $5.3689 |
| Average price | $5.1977 |
| Largest weekly change | +7.7% (Nov 17, 2021) |
| Weeks tracked | 331 |
| Tracking since | Apr 22, 2020 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 86% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DIVIGEL 0.75 MG GEL PACKET?
The current National Average Drug Acquisition Cost (NADAC) for DIVIGEL 0.75 MG GEL PACKET, manufactured by Vertical Pharmaceuticals, LLC, is $5.3993 per EA (NDC 68025008330), effective Aug 19, 2026.
How has the price of DIVIGEL 0.75 MG GEL PACKET changed over time?
Over the history we have for it, the NADAC for DIVIGEL 0.75 MG GEL PACKET has risen 17.1%. It has been tracked across 331 weekly CMS publications since Apr 22, 2020.
What are the highest and lowest recorded NADAC prices for DIVIGEL 0.75 MG GEL PACKET?
Since Apr 22, 2020, the NADAC for DIVIGEL 0.75 MG GEL PACKET has ranged from a low of $4.5350 (Jun 17, 2020) to a high of $5.4151 (Aug 14, 2024), with a median of $5.3689 per EA.
Are there cheaper alternatives to DIVIGEL 0.75 MG GEL PACKET?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ESTRADIOL 0.1% (0.75 MG) GEL PK, is $0.7544 per EA — about 86% below DIVIGEL 0.75 MG GEL PACKET.
Who manufactures DIVIGEL 0.75 MG GEL PACKET?
DIVIGEL 0.75 MG GEL PACKET (NDC 68025008330) is labeled by Vertical Pharmaceuticals, LLC, and CMS classifies it as a brand product.