Product Information
IMVEXXY 4 MCG MAINTENANCE PACK is a brand product labeled by Mayne Pharma, priced at $27.0962 per EA under NDC 68308074708. Its NADAC has been published 110 times since Jul 17, 2024.
FDA first approved this application on May 29, 2018. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the estradiol market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
4 ug/1
Manufacturer
Mayne PharmaNDC
68308074708
Classification
Brand
Dosage Form
INSERT
Route
VAGINAL
Effective Date
6/1/2026
Active Ingredients
ESTRADIOLApproval Type
New Drug (NDA)
FDA Application
NDA208564FDA Approved
5/29/2018
TE Code
AB
On Market Since
5/3/2024
Pharmacological Classes
Price Statistics
The NADAC for IMVEXXY 4 MCG MAINTENANCE PACK has been published 110 times since Jul 17, 2024, and over the history we have for it it has risen 5.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $27.0962 per EA |
|---|---|
| All-time high | $27.0962 (Aug 19, 2026) |
| All-time low | $25.7845 (Feb 18, 2026) |
| 52-week high | $27.0962 |
| 52-week low | $25.7845 |
| Median price | $25.8318 |
| Average price | $25.9623 |
| Largest weekly change | +5.0% (Jun 3, 2026) |
| Weeks tracked | 110 |
| Tracking since | Jul 17, 2024 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of IMVEXXY 4 MCG MAINTENANCE PACK?
The current National Average Drug Acquisition Cost (NADAC) for IMVEXXY 4 MCG MAINTENANCE PACK, manufactured by Mayne Pharma, is $27.0962 per EA (NDC 68308074708), effective Aug 19, 2026.
How has the price of IMVEXXY 4 MCG MAINTENANCE PACK changed over time?
Over the history we have for it, the NADAC for IMVEXXY 4 MCG MAINTENANCE PACK has risen 5.0%. It has been tracked across 110 weekly CMS publications since Jul 17, 2024.
What are the highest and lowest recorded NADAC prices for IMVEXXY 4 MCG MAINTENANCE PACK?
Since Jul 17, 2024, the NADAC for IMVEXXY 4 MCG MAINTENANCE PACK has ranged from a low of $25.7845 (Feb 18, 2026) to a high of $27.0962 (Aug 19, 2026), with a median of $25.8318 per EA.
Are there cheaper alternatives to IMVEXXY 4 MCG MAINTENANCE PACK?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as IMVEXXY 4 MCG MAINTENANCE PACK in a comparable dosage form, but none are currently priced below it.
Who manufactures IMVEXXY 4 MCG MAINTENANCE PACK?
IMVEXXY 4 MCG MAINTENANCE PACK (NDC 68308074708) is labeled by Mayne Pharma, and CMS classifies it as a brand product.