Product Information

IMVEXXY 4 MCG STARTER PACK is a brand product labeled by Mayne Pharma, priced at $27.1090 per EA under NDC 68308074718. Its NADAC has been published 93 times since Nov 13, 2024.

FDA first approved this application on May 29, 2018. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the estradiol market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

IMVEXXY 4 MCG STARTER PACK

estradiol
$27.1090per EA
High Outlier

Strength

4 ug/1

Manufacturer

Mayne Pharma

NDC

68308074718

Classification

Brand

Dosage Form

INSERT

Route

VAGINAL

Effective Date

6/1/2026

Active Ingredients

ESTRADIOL

Approval Type

New Drug (NDA)

FDA Application

NDA208564

FDA Approved

5/29/2018

TE Code

AB

On Market Since

5/3/2024

Pharmacological Classes

Estradiol Congeners
Estrogen Receptor Agonists
Estrogen

Price Statistics

The NADAC for IMVEXXY 4 MCG STARTER PACK has been published 93 times since Nov 13, 2024, and over the history we have for it it has risen 4.6%. The table below summarizes its recorded NADAC range and movement.

Current price$27.1090 per EA
All-time high$27.1090 (Aug 19, 2026)
All-time low$25.8181 (May 20, 2026)
52-week high$27.1090
52-week low$25.8181
Median price$25.8525
Average price$26.0215
Largest weekly change+5.0% (Jun 3, 2026)
Weeks tracked93
Tracking sinceNov 13, 2024

Price History

1W

0.0%

1M

0.0%

3M

+5.0%

6M

+5.0%

1Y

+4.9%

3Y

N/A

5Y

N/A

All

+4.6%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 0% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 0%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of IMVEXXY 4 MCG STARTER PACK?

The current National Average Drug Acquisition Cost (NADAC) for IMVEXXY 4 MCG STARTER PACK, manufactured by Mayne Pharma, is $27.1090 per EA (NDC 68308074718), effective Aug 19, 2026.

How has the price of IMVEXXY 4 MCG STARTER PACK changed over time?

Over the history we have for it, the NADAC for IMVEXXY 4 MCG STARTER PACK has risen 4.6%. It has been tracked across 93 weekly CMS publications since Nov 13, 2024.

What are the highest and lowest recorded NADAC prices for IMVEXXY 4 MCG STARTER PACK?

Since Nov 13, 2024, the NADAC for IMVEXXY 4 MCG STARTER PACK has ranged from a low of $25.8181 (May 20, 2026) to a high of $27.1090 (Aug 19, 2026), with a median of $25.8525 per EA.

Are there cheaper alternatives to IMVEXXY 4 MCG STARTER PACK?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, IMVEXXY 4 MCG MAINTENANCE PACK, is $27.0962 per EA — about 0% below IMVEXXY 4 MCG STARTER PACK.

Who manufactures IMVEXXY 4 MCG STARTER PACK?

IMVEXXY 4 MCG STARTER PACK (NDC 68308074718) is labeled by Mayne Pharma, and CMS classifies it as a brand product.