Product Information
METFORMIN HCL 500 MG TABLET is a generic product labeled by Zydus Pharmaceuticals (USA) Inc., priced at $0.0142 per EA under NDC 68382075805. Its NADAC has been published 572 times since Sep 9, 2015.
FDA first approved this application on Aug 28, 2014. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
500 mg/1
Manufacturer
Zydus Pharmaceuticals (USA) Inc.NDC
68382075805
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
METFORMIN HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA203686FDA Approved
8/28/2014
TE Code
AB
On Market Since
12/9/2014
Pharmacological Classes
Price Statistics
The NADAC for METFORMIN HCL 500 MG TABLET has been published 572 times since Sep 9, 2015, and over the history we have for it it has declined 12.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0142 per EA |
|---|---|
| All-time high | $0.0179 (Jun 15, 2016) |
| All-time low | $0.0123 (Nov 20, 2024) |
| 52-week high | $0.0147 |
| 52-week low | $0.0139 |
| Median price | $0.0158 |
| Average price | $0.0156 |
| Largest weekly change | +20.4% (Jun 19, 2024) |
| Weeks tracked | 572 |
| Tracking since | Sep 9, 2015 |
Generic Alternatives
The matcher finds 10 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 2% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of METFORMIN HCL 500 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for METFORMIN HCL 500 MG TABLET, manufactured by Zydus Pharmaceuticals (USA) Inc., is $0.0142 per EA (NDC 68382075805), effective Aug 19, 2026.
How has the price of METFORMIN HCL 500 MG TABLET changed over time?
Over the history we have for it, the NADAC for METFORMIN HCL 500 MG TABLET has declined 12.5%. It has been tracked across 572 weekly CMS publications since Sep 9, 2015.
What are the highest and lowest recorded NADAC prices for METFORMIN HCL 500 MG TABLET?
Since Sep 9, 2015, the NADAC for METFORMIN HCL 500 MG TABLET has ranged from a low of $0.0123 (Nov 20, 2024) to a high of $0.0179 (Jun 15, 2016), with a median of $0.0158 per EA.
Are there cheaper alternatives to METFORMIN HCL 500 MG TABLET?
Yes. 10 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, METFORMIN HCL 500 MG TABLET, is $0.0140 per EA — about 2% below METFORMIN HCL 500 MG TABLET.
Who manufactures METFORMIN HCL 500 MG TABLET?
METFORMIN HCL 500 MG TABLET (NDC 68382075805) is labeled by Zydus Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.