Product Information
ESOMEPRAZOLE DR 20 MG PACKET is a generic product labeled by Zydus Pharmaceuticals (USA) Inc., priced at $4.0014 per EA under NDC 68382084894. Its NADAC has been published 153 times since Nov 1, 2023.
FDA first approved this application on Jun 7, 2023. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the Esomeprazole Magnesium market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
20 mg/1
Manufacturer
Zydus Pharmaceuticals (USA) Inc.NDC
68382084894
Classification
Generic
Dosage Form
GRANULE, DELAYED RELEASE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
ESOMEPRAZOLE MAGNESIUM DIHYDRATEApproval Type
Generic (ANDA)
FDA Application
ANDA206055FDA Approved
6/7/2023
TE Code
AB
On Market Since
6/30/2023
Pharmacological Classes
Price Statistics
The NADAC for ESOMEPRAZOLE DR 20 MG PACKET has been published 153 times since Nov 1, 2023, and over the history we have for it it has declined 42.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $4.0014 per EA |
|---|---|
| All-time high | $7.2182 (Jan 10, 2024) |
| All-time low | $4.0014 (Sep 23, 2026) |
| 52-week high | $6.2117 |
| 52-week low | $4.0014 |
| Median price | $6.0803 |
| Average price | $6.0764 |
| Largest weekly change | -13.0% (Jul 17, 2024) |
| Weeks tracked | 153 |
| Tracking since | Nov 1, 2023 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Zydus Pharmaceuticals (USA) Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Esomeprazole Magnesium market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Proton Pump Inhibitor class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ESOMEPRAZOLE DR 20 MG PACKET?
The current National Average Drug Acquisition Cost (NADAC) for ESOMEPRAZOLE DR 20 MG PACKET, manufactured by Zydus Pharmaceuticals (USA) Inc., is $4.0014 per EA (NDC 68382084894), effective Sep 30, 2026.
How has the price of ESOMEPRAZOLE DR 20 MG PACKET changed over time?
Over the history we have for it, the NADAC for ESOMEPRAZOLE DR 20 MG PACKET has declined 42.6%. It has been tracked across 153 weekly CMS publications since Nov 1, 2023.
What are the highest and lowest recorded NADAC prices for ESOMEPRAZOLE DR 20 MG PACKET?
Since Nov 1, 2023, the NADAC for ESOMEPRAZOLE DR 20 MG PACKET has ranged from a low of $4.0014 (Sep 23, 2026) to a high of $7.2182 (Jan 10, 2024), with a median of $6.0803 per EA.
Are there cheaper alternatives to ESOMEPRAZOLE DR 20 MG PACKET?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as ESOMEPRAZOLE DR 20 MG PACKET in a comparable dosage form, but none are currently priced below it.
Who manufactures ESOMEPRAZOLE DR 20 MG PACKET?
ESOMEPRAZOLE DR 20 MG PACKET (NDC 68382084894) is labeled by Zydus Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.