Product Information

ESOMEPRAZOLE DR 20 MG PACKET is a generic product labeled by Zydus Pharmaceuticals (USA) Inc., priced at $4.5073 per EA under NDC 68382084894. Its NADAC has been published 147 times since Nov 1, 2023.

FDA first approved this application on Jun 7, 2023. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the Esomeprazole Magnesium market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

ESOMEPRAZOLE DR 20 MG PACKET

Esomeprazole Magnesium
$4.5073per EA
High Outlier

Strength

20 mg/1

NDC

68382084894

Classification

Generic

Dosage Form

GRANULE, DELAYED RELEASE

Route

ORAL

Effective Date

8/19/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA206055

FDA Approved

6/7/2023

TE Code

AB

On Market Since

6/30/2023

Pharmacological Classes

Cytochrome P450 2C19 Inhibitors
Proton Pump Inhibitor
Proton Pump Inhibitors

Price Statistics

The NADAC for ESOMEPRAZOLE DR 20 MG PACKET has been published 147 times since Nov 1, 2023, and over the history we have for it it has declined 35.3%. The table below summarizes its recorded NADAC range and movement.

Current price$4.5073 per EA
All-time high$7.2182 (Jan 10, 2024)
All-time low$4.5073 (Aug 19, 2026)
52-week high$6.2985
52-week low$4.5073
Median price$6.1325
Average price$6.1473
Largest weekly change-13.0% (Jul 17, 2024)
Weeks tracked147
Tracking sinceNov 1, 2023

Price History

1W

-12.4%

1M

-12.4%

3M

-15.2%

6M

-21.6%

1Y

-28.4%

3Y

N/A

5Y

N/A

All

-35.3%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of ESOMEPRAZOLE DR 20 MG PACKET?

The current National Average Drug Acquisition Cost (NADAC) for ESOMEPRAZOLE DR 20 MG PACKET, manufactured by Zydus Pharmaceuticals (USA) Inc., is $4.5073 per EA (NDC 68382084894), effective Aug 19, 2026.

How has the price of ESOMEPRAZOLE DR 20 MG PACKET changed over time?

Over the history we have for it, the NADAC for ESOMEPRAZOLE DR 20 MG PACKET has declined 35.3%. It has been tracked across 147 weekly CMS publications since Nov 1, 2023.

What are the highest and lowest recorded NADAC prices for ESOMEPRAZOLE DR 20 MG PACKET?

Since Nov 1, 2023, the NADAC for ESOMEPRAZOLE DR 20 MG PACKET has ranged from a low of $4.5073 (Aug 19, 2026) to a high of $7.2182 (Jan 10, 2024), with a median of $6.1325 per EA.

Are there cheaper alternatives to ESOMEPRAZOLE DR 20 MG PACKET?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as ESOMEPRAZOLE DR 20 MG PACKET in a comparable dosage form, but none are currently priced below it.

Who manufactures ESOMEPRAZOLE DR 20 MG PACKET?

ESOMEPRAZOLE DR 20 MG PACKET (NDC 68382084894) is labeled by Zydus Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.