Product Information
CLOBETASOL PROP 0.05% SPRAY is a generic product labeled by Zydus Pharmaceuticals (USA) Inc., priced at $0.3427 per ML under NDC 68382099801. Its NADAC has been published 381 times since May 8, 2019.
FDA first approved this application on Feb 16, 2017. Its Orange Book therapeutic-equivalence code is AT.
Strength
.05 g/mL
Manufacturer
Zydus Pharmaceuticals (USA) Inc.NDC
68382099801
Classification
Generic
Dosage Form
SPRAY
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
CLOBETASOL PROPIONATEApproval Type
Generic (ANDA)
FDA Application
ANDA206378FDA Approved
2/16/2017
TE Code
AT
On Market Since
7/12/2017
Pharmacological Classes
Price Statistics
The NADAC for CLOBETASOL PROP 0.05% SPRAY has been published 381 times since May 8, 2019, and over the history we have for it it has declined 76.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3427 per ML |
|---|---|
| All-time high | $1.9802 (Oct 16, 2019) |
| All-time low | $0.2926 (Apr 17, 2024) |
| 52-week high | $0.3981 |
| 52-week low | $0.3356 |
| Median price | $0.4622 |
| Average price | $0.6069 |
| Largest weekly change | +58.2% (Dec 22, 2021) |
| Weeks tracked | 381 |
| Tracking since | May 8, 2019 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 26% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of CLOBETASOL PROP 0.05% SPRAY?
The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL PROP 0.05% SPRAY, manufactured by Zydus Pharmaceuticals (USA) Inc., is $0.3427 per ML (NDC 68382099801), effective Aug 19, 2026.
How has the price of CLOBETASOL PROP 0.05% SPRAY changed over time?
Over the history we have for it, the NADAC for CLOBETASOL PROP 0.05% SPRAY has declined 76.5%. It has been tracked across 381 weekly CMS publications since May 8, 2019.
What are the highest and lowest recorded NADAC prices for CLOBETASOL PROP 0.05% SPRAY?
Since May 8, 2019, the NADAC for CLOBETASOL PROP 0.05% SPRAY has ranged from a low of $0.2926 (Apr 17, 2024) to a high of $1.9802 (Oct 16, 2019), with a median of $0.4622 per ML.
Are there cheaper alternatives to CLOBETASOL PROP 0.05% SPRAY?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CLOBETASOL PROP 0.05% SPRAY, is $0.2529 per ML — about 26% below CLOBETASOL PROP 0.05% SPRAY.
Who manufactures CLOBETASOL PROP 0.05% SPRAY?
CLOBETASOL PROP 0.05% SPRAY (NDC 68382099801) is labeled by Zydus Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.