Product Information

CLOBETASOL PROP 0.05% SPRAY is a generic product labeled by Zydus Pharmaceuticals (USA) Inc., priced at $0.3507 per ML under NDC 68382099801. Its NADAC has been published 373 times since May 8, 2019.

CLOBETASOL PROP 0.05% SPRAY

clobetasol propionate
$0.3507per ML

Strength

.05 g/mL

NDC

68382099801

Classification

Generic

Dosage Form

SPRAY

Route

TOPICAL

Last Updated

6/17/2026

Active Ingredients

CLOBETASOL PROPIONATE

Approval Type

Generic (ANDA)

FDA Application

ANDA206378

On Market Since

7/12/2017

Pharmacological Classes

Corticosteroid Hormone Receptor Agonists
Corticosteroid

Price Statistics

The NADAC for CLOBETASOL PROP 0.05% SPRAY has been published 373 times since May 8, 2019, and over the history we have for it it has declined 76.0%. The table below summarizes its recorded NADAC range and movement.

Current price$0.3507 per ML
All-time high$1.9802 (Oct 16, 2019)
All-time low$0.2926 (Apr 17, 2024)
52-week high$0.4019
52-week low$0.3410
Median price$0.4622
Average price$0.6126
Largest weekly change+58.2% (Dec 22, 2021)
Weeks tracked373
Tracking sinceMay 8, 2019

Price History

1W

0.0%

1M

-9.2%

3M

-0.6%

6M

-6.6%

1Y

-12.7%

3Y

-33.5%

5Y

+16.8%

All

-76.0%

Generic Alternatives

The matcher finds 3 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 3 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 33% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of CLOBETASOL PROP 0.05% SPRAY?

The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL PROP 0.05% SPRAY, manufactured by Zydus Pharmaceuticals (USA) Inc., is $0.3507 per ML (NDC 68382099801), effective Jun 24, 2026.

How has the price of CLOBETASOL PROP 0.05% SPRAY changed over time?

Over the history we have for it, the NADAC for CLOBETASOL PROP 0.05% SPRAY has declined 76.0%. It has been tracked across 373 weekly CMS publications since May 8, 2019.

What are the highest and lowest recorded NADAC prices for CLOBETASOL PROP 0.05% SPRAY?

Since May 8, 2019, the NADAC for CLOBETASOL PROP 0.05% SPRAY has ranged from a low of $0.2926 (Apr 17, 2024) to a high of $1.9802 (Oct 16, 2019), with a median of $0.4622 per ML.

Are there cheaper alternatives to CLOBETASOL PROP 0.05% SPRAY?

Yes. 3 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, CLOBETASOL 0.05% SHAMPOO, is $0.2333 per ML — about 33% below CLOBETASOL PROP 0.05% SPRAY.

Who manufactures CLOBETASOL PROP 0.05% SPRAY?

CLOBETASOL PROP 0.05% SPRAY (NDC 68382099801) is labeled by Zydus Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.