Product Information
CLOBETASOL PROP 0.05% SPRAY is a generic product labeled by Zydus Pharmaceuticals (USA) Inc., priced at $0.2480 per ML under NDC 68382099802. Its NADAC has been published 387 times since May 8, 2019.
FDA first approved this application on Feb 16, 2017. Its Orange Book therapeutic-equivalence code is AT.
Strength
.05 g/mL
Manufacturer
Zydus Pharmaceuticals (USA) Inc.NDC
68382099802
Classification
Generic
Dosage Form
SPRAY
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
CLOBETASOL PROPIONATEApproval Type
Generic (ANDA)
FDA Application
ANDA206378FDA Approved
2/16/2017
TE Code
AT
On Market Since
7/12/2017
Pharmacological Classes
Price Statistics
The NADAC for CLOBETASOL PROP 0.05% SPRAY has been published 387 times since May 8, 2019, and over the history we have for it it has declined 70.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2480 per ML |
|---|---|
| All-time high | $1.2874 (Aug 14, 2019) |
| All-time low | $0.1603 (Mar 22, 2023) |
| 52-week high | $0.3327 |
| 52-week low | $0.2480 |
| Median price | $0.3327 |
| Average price | $0.4637 |
| Largest weekly change | +145.7% (Jul 21, 2021) |
| Weeks tracked | 387 |
| Tracking since | May 8, 2019 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Zydus Pharmaceuticals (USA) Inc. manufacturer profile
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Drug market
clobetasol propionate market comparison
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Therapeutic class
Corticosteroid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of CLOBETASOL PROP 0.05% SPRAY?
The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL PROP 0.05% SPRAY, manufactured by Zydus Pharmaceuticals (USA) Inc., is $0.2480 per ML (NDC 68382099802), effective Sep 30, 2026.
How has the price of CLOBETASOL PROP 0.05% SPRAY changed over time?
Over the history we have for it, the NADAC for CLOBETASOL PROP 0.05% SPRAY has declined 70.0%. It has been tracked across 387 weekly CMS publications since May 8, 2019.
What are the highest and lowest recorded NADAC prices for CLOBETASOL PROP 0.05% SPRAY?
Since May 8, 2019, the NADAC for CLOBETASOL PROP 0.05% SPRAY has ranged from a low of $0.1603 (Mar 22, 2023) to a high of $1.2874 (Aug 14, 2019), with a median of $0.3327 per ML.
Are there cheaper alternatives to CLOBETASOL PROP 0.05% SPRAY?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as CLOBETASOL PROP 0.05% SPRAY in a comparable dosage form, but none are currently priced below it.
Who manufactures CLOBETASOL PROP 0.05% SPRAY?
CLOBETASOL PROP 0.05% SPRAY (NDC 68382099802) is labeled by Zydus Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.