Product Information

CLOBETASOL PROP 0.05% SPRAY is a generic product labeled by Zydus Pharmaceuticals (USA) Inc., priced at $0.2806 per ML under NDC 68382099802. Its NADAC has been published 373 times since May 8, 2019.

CLOBETASOL PROP 0.05% SPRAY

clobetasol propionate
$0.2806per ML

Strength

.05 g/mL

NDC

68382099802

Classification

Generic

Dosage Form

SPRAY

Route

TOPICAL

Last Updated

6/17/2026

Active Ingredients

CLOBETASOL PROPIONATE

Approval Type

Generic (ANDA)

FDA Application

ANDA206378

On Market Since

7/12/2017

Pharmacological Classes

Corticosteroid Hormone Receptor Agonists
Corticosteroid

Price Statistics

The NADAC for CLOBETASOL PROP 0.05% SPRAY has been published 373 times since May 8, 2019, and over the history we have for it it has declined 66.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.2806 per ML
All-time high$1.2874 (Aug 14, 2019)
All-time low$0.1603 (Mar 22, 2023)
52-week high$0.3327
52-week low$0.2394
Median price$0.3631
Average price$0.4711
Largest weekly change+145.7% (Jul 21, 2021)
Weeks tracked373
Tracking sinceMay 8, 2019

Price History

1W

0.0%

1M

+0.1%

3M

+3.1%

6M

-11.1%

1Y

+17.2%

3Y

+75.0%

5Y

+33.9%

All

-66.1%

Generic Alternatives

The matcher finds 3 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 3 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 17% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of CLOBETASOL PROP 0.05% SPRAY?

The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL PROP 0.05% SPRAY, manufactured by Zydus Pharmaceuticals (USA) Inc., is $0.2806 per ML (NDC 68382099802), effective Jun 24, 2026.

How has the price of CLOBETASOL PROP 0.05% SPRAY changed over time?

Over the history we have for it, the NADAC for CLOBETASOL PROP 0.05% SPRAY has declined 66.1%. It has been tracked across 373 weekly CMS publications since May 8, 2019.

What are the highest and lowest recorded NADAC prices for CLOBETASOL PROP 0.05% SPRAY?

Since May 8, 2019, the NADAC for CLOBETASOL PROP 0.05% SPRAY has ranged from a low of $0.1603 (Mar 22, 2023) to a high of $1.2874 (Aug 14, 2019), with a median of $0.3631 per ML.

Are there cheaper alternatives to CLOBETASOL PROP 0.05% SPRAY?

Yes. 3 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, CLOBETASOL 0.05% SHAMPOO, is $0.2333 per ML — about 17% below CLOBETASOL PROP 0.05% SPRAY.

Who manufactures CLOBETASOL PROP 0.05% SPRAY?

CLOBETASOL PROP 0.05% SPRAY (NDC 68382099802) is labeled by Zydus Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.