Product Information
BRIMONIDINE-TIMOLOL 0.2%-0.5% is a generic product labeled by Glenmark Pharmaceuticals Inc., USA, priced at $2.7175 per ML under NDC 68462028169. Its NADAC has been published 118 times since Jul 3, 2024.
FDA first approved this application on May 16, 2024. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the Brimonidine Tartrate and Timolol Maleate market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
2; 5 mg/mL; mg/mL
Manufacturer
Glenmark Pharmaceuticals Inc., USANDC
68462028169
Classification
Generic
Dosage Form
SOLUTION/ DROPS
Route
OPHTHALMIC
Effective Date
9/23/2026
Active Ingredients
BRIMONIDINE TARTRATE; TIMOLOL MALEATEApproval Type
Generic (ANDA)
FDA Application
ANDA214987FDA Approved
5/16/2024
TE Code
AB
On Market Since
5/16/2024
Pharmacological Classes
Price Statistics
The NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has been published 118 times since Jul 3, 2024, and over the history we have for it it has declined 75.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.7175 per ML |
|---|---|
| All-time high | $11.2842 (Jul 10, 2024) |
| All-time low | $2.7175 (Sep 23, 2026) |
| 52-week high | $4.4337 |
| 52-week low | $2.7175 |
| Median price | $4.9566 |
| Average price | $5.0796 |
| Largest weekly change | -37.2% (Jul 17, 2024) |
| Weeks tracked | 118 |
| Tracking since | Jul 3, 2024 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 27% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Glenmark Pharmaceuticals Inc., USA manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Brimonidine Tartrate and Timolol Maleate market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
alpha-Adrenergic Agonist class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of BRIMONIDINE-TIMOLOL 0.2%-0.5%?
The current National Average Drug Acquisition Cost (NADAC) for BRIMONIDINE-TIMOLOL 0.2%-0.5%, manufactured by Glenmark Pharmaceuticals Inc., USA, is $2.7175 per ML (NDC 68462028169), effective Sep 30, 2026.
How has the price of BRIMONIDINE-TIMOLOL 0.2%-0.5% changed over time?
Over the history we have for it, the NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has declined 75.9%. It has been tracked across 118 weekly CMS publications since Jul 3, 2024.
What are the highest and lowest recorded NADAC prices for BRIMONIDINE-TIMOLOL 0.2%-0.5%?
Since Jul 3, 2024, the NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has ranged from a low of $2.7175 (Sep 23, 2026) to a high of $11.2842 (Jul 10, 2024), with a median of $4.9566 per ML.
Are there cheaper alternatives to BRIMONIDINE-TIMOLOL 0.2%-0.5%?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, BRIMONIDINE-TIMOLOL 0.2%-0.5%, is $1.9717 per ML — about 27% below BRIMONIDINE-TIMOLOL 0.2%-0.5%.
Who manufactures BRIMONIDINE-TIMOLOL 0.2%-0.5%?
BRIMONIDINE-TIMOLOL 0.2%-0.5% (NDC 68462028169) is labeled by Glenmark Pharmaceuticals Inc., USA, and CMS classifies it as a generic product.