Product Information

ESTRADIOL 0.1% (1 MG) GEL PKT is a generic product labeled by Amneal Pharmaceuticals NY LLC, priced at $1.1272 per GM under NDC 69238244903. Its NADAC has been published 86 times since Jan 1, 2025.

FDA first approved this application on Jul 12, 2024. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

ESTRADIOL 0.1% (1 MG) GEL PKT

Estradiol Transdermal
$1.1272per GM

Strength

1 mg/g

NDC

69238244903

Classification

Generic

Dosage Form

GEL

Route

TOPICAL

Effective Date

8/19/2026

Active Ingredients

ESTRADIOL

Approval Type

Generic (ANDA)

FDA Application

ANDA216055

FDA Approved

7/12/2024

TE Code

AB

On Market Since

7/15/2024

Pharmacological Classes

Estradiol Congeners
Estrogen Receptor Agonists
Estrogen

Price Statistics

The NADAC for ESTRADIOL 0.1% (1 MG) GEL PKT has been published 86 times since Jan 1, 2025, and over the history we have for it it has declined 39.7%. The table below summarizes its recorded NADAC range and movement.

Current price$1.1272 per GM
All-time high$2.1298 (Jul 16, 2025)
All-time low$1.1272 (Aug 19, 2026)
52-week high$2.0960
52-week low$1.1272
Median price$1.8220
Average price$1.7952
Largest weekly change-15.1% (Jul 22, 2026)
Weeks tracked86
Tracking sinceJan 1, 2025

Price History

1W

-12.0%

1M

-12.0%

3M

-33.6%

6M

-24.3%

1Y

-46.2%

3Y

N/A

5Y

N/A

All

-39.7%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Estradiol Transdermal market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Frequently asked questions

What is the NADAC price of ESTRADIOL 0.1% (1 MG) GEL PKT?

The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL 0.1% (1 MG) GEL PKT, manufactured by Amneal Pharmaceuticals NY LLC, is $1.1272 per GM (NDC 69238244903), effective Aug 19, 2026.

How has the price of ESTRADIOL 0.1% (1 MG) GEL PKT changed over time?

Over the history we have for it, the NADAC for ESTRADIOL 0.1% (1 MG) GEL PKT has declined 39.7%. It has been tracked across 86 weekly CMS publications since Jan 1, 2025.

What are the highest and lowest recorded NADAC prices for ESTRADIOL 0.1% (1 MG) GEL PKT?

Since Jan 1, 2025, the NADAC for ESTRADIOL 0.1% (1 MG) GEL PKT has ranged from a low of $1.1272 (Aug 19, 2026) to a high of $2.1298 (Jul 16, 2025), with a median of $1.8220 per GM.

Are there cheaper alternatives to ESTRADIOL 0.1% (1 MG) GEL PKT?

No other NADAC-published product currently shares the active ingredient and strength of ESTRADIOL 0.1% (1 MG) GEL PKT in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures ESTRADIOL 0.1% (1 MG) GEL PKT?

ESTRADIOL 0.1% (1 MG) GEL PKT (NDC 69238244903) is labeled by Amneal Pharmaceuticals NY LLC, and CMS classifies it as a generic product.