Product Information
ESTRADIOL 0.1% (0.5 MG) GEL PKT is a generic product labeled by Amneal Pharmaceuticals NY LLC, priced at $1.0336 per EA under NDC 69238245103. Its NADAC has been published 86 times since Jan 1, 2025.
FDA first approved this application on Jul 12, 2024. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
.5 mg/.5g
Manufacturer
Amneal Pharmaceuticals NY LLCNDC
69238245103
Classification
Generic
Dosage Form
GEL
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
ESTRADIOLApproval Type
Generic (ANDA)
FDA Application
ANDA216055FDA Approved
7/12/2024
TE Code
AB
On Market Since
7/15/2024
Pharmacological Classes
Price Statistics
The NADAC for ESTRADIOL 0.1% (0.5 MG) GEL PKT has been published 86 times since Jan 1, 2025, and over the history we have for it it has declined 34.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.0336 per EA |
|---|---|
| All-time high | $2.1810 (Jul 16, 2025) |
| All-time low | $1.0336 (Aug 19, 2026) |
| 52-week high | $2.1669 |
| 52-week low | $1.0336 |
| Median price | $1.8372 |
| Average price | $1.7576 |
| Largest weekly change | -17.4% (Aug 19, 2026) |
| Weeks tracked | 86 |
| Tracking since | Jan 1, 2025 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Estradiol Transdermal market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ESTRADIOL 0.1% (0.5 MG) GEL PKT?
The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL 0.1% (0.5 MG) GEL PKT, manufactured by Amneal Pharmaceuticals NY LLC, is $1.0336 per EA (NDC 69238245103), effective Aug 19, 2026.
How has the price of ESTRADIOL 0.1% (0.5 MG) GEL PKT changed over time?
Over the history we have for it, the NADAC for ESTRADIOL 0.1% (0.5 MG) GEL PKT has declined 34.9%. It has been tracked across 86 weekly CMS publications since Jan 1, 2025.
What are the highest and lowest recorded NADAC prices for ESTRADIOL 0.1% (0.5 MG) GEL PKT?
Since Jan 1, 2025, the NADAC for ESTRADIOL 0.1% (0.5 MG) GEL PKT has ranged from a low of $1.0336 (Aug 19, 2026) to a high of $2.1810 (Jul 16, 2025), with a median of $1.8372 per EA.
Are there cheaper alternatives to ESTRADIOL 0.1% (0.5 MG) GEL PKT?
No other NADAC-published product currently shares the active ingredient and strength of ESTRADIOL 0.1% (0.5 MG) GEL PKT in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures ESTRADIOL 0.1% (0.5 MG) GEL PKT?
ESTRADIOL 0.1% (0.5 MG) GEL PKT (NDC 69238245103) is labeled by Amneal Pharmaceuticals NY LLC, and CMS classifies it as a generic product.