Product Information

ESTRADIOL 0.1% (0.5 MG) GEL PKT is a generic product labeled by Amneal Pharmaceuticals NY LLC, priced at $1.3243 per EA under NDC 69238245103. Its NADAC has been published 78 times since Jan 1, 2025.

ESTRADIOL 0.1% (0.5 MG) GEL PKT

Estradiol Transdermal
$1.3243per EA

Strength

.5 mg/.5g

NDC

69238245103

Classification

Generic

Dosage Form

GEL

Route

TOPICAL

Last Updated

6/17/2026

Active Ingredients

ESTRADIOL

Approval Type

Generic (ANDA)

FDA Application

ANDA216055

On Market Since

7/15/2024

Pharmacological Classes

Estradiol Congeners
Estrogen Receptor Agonists
Estrogen

Price Statistics

The NADAC for ESTRADIOL 0.1% (0.5 MG) GEL PKT has been published 78 times since Jan 1, 2025, and over the history we have for it it has declined 16.5%. The table below summarizes its recorded NADAC range and movement.

Current price$1.3243 per EA
All-time high$2.1810 (Jul 16, 2025)
All-time low$1.3243 (Jun 17, 2026)
52-week high$2.1810
52-week low$1.3243
Median price$1.8579
Average price$1.8095
Largest weekly change+12.9% (Feb 19, 2025)
Weeks tracked78
Tracking sinceJan 1, 2025

Price History

1W

0.0%

1M

-3.1%

3M

-11.7%

6M

-27.9%

1Y

-39.3%

3Y

N/A

5Y

N/A

All

-16.5%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient, strength, and dosage form. Compare the broader picture on the Estradiol Transdermal market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient, strength, and dosage form.

Frequently asked questions

What is the NADAC price of ESTRADIOL 0.1% (0.5 MG) GEL PKT?

The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL 0.1% (0.5 MG) GEL PKT, manufactured by Amneal Pharmaceuticals NY LLC, is $1.3243 per EA (NDC 69238245103), effective Jun 24, 2026.

How has the price of ESTRADIOL 0.1% (0.5 MG) GEL PKT changed over time?

Over the history we have for it, the NADAC for ESTRADIOL 0.1% (0.5 MG) GEL PKT has declined 16.5%. It has been tracked across 78 weekly CMS publications since Jan 1, 2025.

What are the highest and lowest recorded NADAC prices for ESTRADIOL 0.1% (0.5 MG) GEL PKT?

Since Jan 1, 2025, the NADAC for ESTRADIOL 0.1% (0.5 MG) GEL PKT has ranged from a low of $1.3243 (Jun 17, 2026) to a high of $2.1810 (Jul 16, 2025), with a median of $1.8579 per EA.

Are there cheaper alternatives to ESTRADIOL 0.1% (0.5 MG) GEL PKT?

No other NADAC-published product currently shares the active ingredient, strength, and dosage form of ESTRADIOL 0.1% (0.5 MG) GEL PKT, so no direct lower-cost alternative is listed.

Who manufactures ESTRADIOL 0.1% (0.5 MG) GEL PKT?

ESTRADIOL 0.1% (0.5 MG) GEL PKT (NDC 69238245103) is labeled by Amneal Pharmaceuticals NY LLC, and CMS classifies it as a generic product.