Product Information

ESTRADIOL 0.1% (0.25 MG) GEL PK is a generic product labeled by Amneal Pharmaceuticals NY LLC, priced at $1.3810 per EA under NDC 69238245203. Its NADAC has been published 73 times since Feb 5, 2025.

ESTRADIOL 0.1% (0.25 MG) GEL PK

Estradiol Transdermal
$1.3810per EA

Strength

.25 mg/.25g

NDC

69238245203

Classification

Generic

Dosage Form

GEL

Route

TOPICAL

Last Updated

6/17/2026

Active Ingredients

ESTRADIOL

Approval Type

Generic (ANDA)

FDA Application

ANDA216055

On Market Since

7/15/2024

Pharmacological Classes

Estradiol Congeners
Estrogen Receptor Agonists
Estrogen

Price Statistics

The NADAC for ESTRADIOL 0.1% (0.25 MG) GEL PK has been published 73 times since Feb 5, 2025, and over the history we have for it it has declined 12.6%. The table below summarizes its recorded NADAC range and movement.

Current price$1.3810 per EA
All-time high$2.0942 (Aug 13, 2025)
All-time low$1.3810 (Jun 17, 2026)
52-week high$2.0942
52-week low$1.3810
Median price$1.7501
Average price$1.7872
Largest weekly change+11.5% (Mar 19, 2025)
Weeks tracked73
Tracking sinceFeb 5, 2025

Price History

1W

0.0%

1M

-6.9%

3M

-9.3%

6M

-19.1%

1Y

-32.6%

3Y

N/A

5Y

N/A

All

-12.6%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient, strength, and dosage form. Compare the broader picture on the Estradiol Transdermal market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient, strength, and dosage form.

Frequently asked questions

What is the NADAC price of ESTRADIOL 0.1% (0.25 MG) GEL PK?

The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL 0.1% (0.25 MG) GEL PK, manufactured by Amneal Pharmaceuticals NY LLC, is $1.3810 per EA (NDC 69238245203), effective Jun 24, 2026.

How has the price of ESTRADIOL 0.1% (0.25 MG) GEL PK changed over time?

Over the history we have for it, the NADAC for ESTRADIOL 0.1% (0.25 MG) GEL PK has declined 12.6%. It has been tracked across 73 weekly CMS publications since Feb 5, 2025.

What are the highest and lowest recorded NADAC prices for ESTRADIOL 0.1% (0.25 MG) GEL PK?

Since Feb 5, 2025, the NADAC for ESTRADIOL 0.1% (0.25 MG) GEL PK has ranged from a low of $1.3810 (Jun 17, 2026) to a high of $2.0942 (Aug 13, 2025), with a median of $1.7501 per EA.

Are there cheaper alternatives to ESTRADIOL 0.1% (0.25 MG) GEL PK?

No other NADAC-published product currently shares the active ingredient, strength, and dosage form of ESTRADIOL 0.1% (0.25 MG) GEL PK, so no direct lower-cost alternative is listed.

Who manufactures ESTRADIOL 0.1% (0.25 MG) GEL PK?

ESTRADIOL 0.1% (0.25 MG) GEL PK (NDC 69238245203) is labeled by Amneal Pharmaceuticals NY LLC, and CMS classifies it as a generic product.