Product Information
ACYCLOVIR 5% OINTMENT is a generic product labeled by Xiromed LLC, priced at $0.3458 per GM under NDC 70700010716. Its NADAC has been published 330 times since Jun 10, 2020.
FDA first approved this application on Jan 29, 2020. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/g
Manufacturer
Xiromed LLCNDC
70700010716
Classification
Generic
Dosage Form
OINTMENT
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
ACYCLOVIRApproval Type
Generic (ANDA)
FDA Application
ANDA201501FDA Approved
1/29/2020
TE Code
AB
On Market Since
1/30/2020
Pharmacological Classes
Price Statistics
The NADAC for ACYCLOVIR 5% OINTMENT has been published 330 times since Jun 10, 2020, and over the history we have for it it has declined 73.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3458 per GM |
|---|---|
| All-time high | $1.9980 (Aug 11, 2021) |
| All-time low | $0.3058 (Jul 22, 2026) |
| 52-week high | $0.4109 |
| 52-week low | $0.3058 |
| Median price | $0.6088 |
| Average price | $0.7532 |
| Largest weekly change | +89.1% (Jun 23, 2021) |
| Weeks tracked | 330 |
| Tracking since | Jun 10, 2020 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Xiromed LLC manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Acyclovir market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ACYCLOVIR 5% OINTMENT?
The current National Average Drug Acquisition Cost (NADAC) for ACYCLOVIR 5% OINTMENT, manufactured by Xiromed LLC, is $0.3458 per GM (NDC 70700010716), effective Sep 30, 2026.
How has the price of ACYCLOVIR 5% OINTMENT changed over time?
Over the history we have for it, the NADAC for ACYCLOVIR 5% OINTMENT has declined 73.0%. It has been tracked across 330 weekly CMS publications since Jun 10, 2020.
What are the highest and lowest recorded NADAC prices for ACYCLOVIR 5% OINTMENT?
Since Jun 10, 2020, the NADAC for ACYCLOVIR 5% OINTMENT has ranged from a low of $0.3058 (Jul 22, 2026) to a high of $1.9980 (Aug 11, 2021), with a median of $0.6088 per GM.
Are there cheaper alternatives to ACYCLOVIR 5% OINTMENT?
5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ACYCLOVIR 5% OINTMENT in a comparable dosage form, but none are currently priced below it.
Who manufactures ACYCLOVIR 5% OINTMENT?
ACYCLOVIR 5% OINTMENT (NDC 70700010716) is labeled by Xiromed LLC, and CMS classifies it as a generic product.