Product Information
ACYCLOVIR 5% OINTMENT is a generic product labeled by Amneal Pharmaceuticals LLC, priced at $0.3421 per GM under NDC 65162083596. Its NADAC has been published 634 times since Jul 2, 2014.
FDA first approved this application on Jun 18, 2014. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the Acyclovir market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
50 mg/g
Manufacturer
Amneal Pharmaceuticals LLCNDC
65162083596
Classification
Generic
Dosage Form
OINTMENT
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
ACYCLOVIRApproval Type
Generic (ANDA)
FDA Application
ANDA204605FDA Approved
6/18/2014
TE Code
AB
On Market Since
1/3/2014
Pharmacological Classes
Price Statistics
The NADAC for ACYCLOVIR 5% OINTMENT has been published 634 times since Jul 2, 2014, and over the history we have for it it has declined 98.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3421 per GM |
|---|---|
| All-time high | $17.3294 (Aug 13, 2014) |
| All-time low | $0.3058 (Jul 22, 2026) |
| 52-week high | $0.4469 |
| 52-week low | $0.3058 |
| Median price | $1.5205 |
| Average price | $4.5274 |
| Largest weekly change | +89.1% (Jun 23, 2021) |
| Weeks tracked | 634 |
| Tracking since | Jul 2, 2014 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ACYCLOVIR 5% OINTMENT?
The current National Average Drug Acquisition Cost (NADAC) for ACYCLOVIR 5% OINTMENT, manufactured by Amneal Pharmaceuticals LLC, is $0.3421 per GM (NDC 65162083596), effective Aug 19, 2026.
How has the price of ACYCLOVIR 5% OINTMENT changed over time?
Over the history we have for it, the NADAC for ACYCLOVIR 5% OINTMENT has declined 98.0%. It has been tracked across 634 weekly CMS publications since Jul 2, 2014.
What are the highest and lowest recorded NADAC prices for ACYCLOVIR 5% OINTMENT?
Since Jul 2, 2014, the NADAC for ACYCLOVIR 5% OINTMENT has ranged from a low of $0.3058 (Jul 22, 2026) to a high of $17.3294 (Aug 13, 2014), with a median of $1.5205 per GM.
Are there cheaper alternatives to ACYCLOVIR 5% OINTMENT?
5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ACYCLOVIR 5% OINTMENT in a comparable dosage form, but none are currently priced below it.
Who manufactures ACYCLOVIR 5% OINTMENT?
ACYCLOVIR 5% OINTMENT (NDC 65162083596) is labeled by Amneal Pharmaceuticals LLC, and CMS classifies it as a generic product.