Product Information
ACYCLOVIR 5% OINTMENT is a generic product labeled by Macleods Pharmaceuticals Limited, priced at $0.3421 per GM under NDC 33342043930. Its NADAC has been published 217 times since Feb 23, 2022.
FDA first approved this application on May 19, 2021. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/g
Manufacturer
Macleods Pharmaceuticals LimitedNDC
33342043930
Classification
Generic
Dosage Form
OINTMENT
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
ACYCLOVIRApproval Type
Generic (ANDA)
FDA Application
ANDA212444FDA Approved
5/19/2021
TE Code
AB
On Market Since
8/13/2018
Pharmacological Classes
Price Statistics
The NADAC for ACYCLOVIR 5% OINTMENT has been published 217 times since Feb 23, 2022, and over the history we have for it it has declined 68.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3421 per GM |
|---|---|
| All-time high | $1.1763 (May 11, 2022) |
| All-time low | $0.3058 (Jul 22, 2026) |
| 52-week high | $0.4469 |
| 52-week low | $0.3058 |
| Median price | $0.4583 |
| Average price | $0.5390 |
| Largest weekly change | +55.3% (Feb 21, 2024) |
| Weeks tracked | 217 |
| Tracking since | Feb 23, 2022 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ACYCLOVIR 5% OINTMENT?
The current National Average Drug Acquisition Cost (NADAC) for ACYCLOVIR 5% OINTMENT, manufactured by Macleods Pharmaceuticals Limited, is $0.3421 per GM (NDC 33342043930), effective Aug 19, 2026.
How has the price of ACYCLOVIR 5% OINTMENT changed over time?
Over the history we have for it, the NADAC for ACYCLOVIR 5% OINTMENT has declined 68.8%. It has been tracked across 217 weekly CMS publications since Feb 23, 2022.
What are the highest and lowest recorded NADAC prices for ACYCLOVIR 5% OINTMENT?
Since Feb 23, 2022, the NADAC for ACYCLOVIR 5% OINTMENT has ranged from a low of $0.3058 (Jul 22, 2026) to a high of $1.1763 (May 11, 2022), with a median of $0.4583 per GM.
Are there cheaper alternatives to ACYCLOVIR 5% OINTMENT?
5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ACYCLOVIR 5% OINTMENT in a comparable dosage form, but none are currently priced below it.
Who manufactures ACYCLOVIR 5% OINTMENT?
ACYCLOVIR 5% OINTMENT (NDC 33342043930) is labeled by Macleods Pharmaceuticals Limited, and CMS classifies it as a generic product.