Product Information

ESTRADIOL 0.1% (1.25 MG) GEL PK is a generic product labeled by Xiromed LLC, priced at $1.1440 per GM under NDC 70700019535. Its NADAC has been published 123 times since Feb 21, 2024.

ESTRADIOL 0.1% (1.25 MG) GEL PK

Estradiol Gel 0.1%
$1.1440per GM

Strength

1.25 mg/1.25g

Manufacturer

Xiromed LLC

NDC

70700019535

Classification

Generic

Dosage Form

GEL

Route

TOPICAL

Last Updated

6/17/2026

Active Ingredients

ESTRADIOL

Approval Type

Generic (ANDA)

FDA Application

ANDA211783

On Market Since

10/1/2022

Pharmacological Classes

Estradiol Congeners
Estrogen Receptor Agonists
Estrogen

Price Statistics

The NADAC for ESTRADIOL 0.1% (1.25 MG) GEL PK has been published 123 times since Feb 21, 2024, and over the history we have for it it has declined 54.3%. The table below summarizes its recorded NADAC range and movement.

Current price$1.1440 per GM
All-time high$2.8779 (Jun 12, 2024)
All-time low$1.1366 (Apr 22, 2026)
52-week high$1.7813
52-week low$1.1366
Median price$1.5881
Average price$1.6645
Largest weekly change-30.5% (Jun 19, 2024)
Weeks tracked123
Tracking sinceFeb 21, 2024

Price History

1W

0.0%

1M

-1.7%

3M

-3.3%

6M

-18.2%

1Y

-28.6%

3Y

N/A

5Y

N/A

All

-54.3%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient, strength, and dosage form. Compare the broader picture on the Estradiol Gel 0.1% market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient, strength, and dosage form.

Frequently asked questions

What is the NADAC price of ESTRADIOL 0.1% (1.25 MG) GEL PK?

The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL 0.1% (1.25 MG) GEL PK, manufactured by Xiromed LLC, is $1.1440 per GM (NDC 70700019535), effective Jun 24, 2026.

How has the price of ESTRADIOL 0.1% (1.25 MG) GEL PK changed over time?

Over the history we have for it, the NADAC for ESTRADIOL 0.1% (1.25 MG) GEL PK has declined 54.3%. It has been tracked across 123 weekly CMS publications since Feb 21, 2024.

What are the highest and lowest recorded NADAC prices for ESTRADIOL 0.1% (1.25 MG) GEL PK?

Since Feb 21, 2024, the NADAC for ESTRADIOL 0.1% (1.25 MG) GEL PK has ranged from a low of $1.1366 (Apr 22, 2026) to a high of $2.8779 (Jun 12, 2024), with a median of $1.5881 per GM.

Are there cheaper alternatives to ESTRADIOL 0.1% (1.25 MG) GEL PK?

No other NADAC-published product currently shares the active ingredient, strength, and dosage form of ESTRADIOL 0.1% (1.25 MG) GEL PK, so no direct lower-cost alternative is listed.

Who manufactures ESTRADIOL 0.1% (1.25 MG) GEL PK?

ESTRADIOL 0.1% (1.25 MG) GEL PK (NDC 70700019535) is labeled by Xiromed LLC, and CMS classifies it as a generic product.