Product Information
ESTRADIOL VALERATE 100 MG/5 ML is a generic product labeled by Xiromed LLC, priced at $22.6452 per ML under NDC 70700027422. Its NADAC has been published 169 times since Jul 12, 2023.
FDA first approved this application on Apr 28, 2023. Its Orange Book therapeutic-equivalence code is AO.
Strength
20 mg/mL
Manufacturer
Xiromed LLCNDC
70700027422
Classification
Generic
Dosage Form
INJECTION
Route
INTRAMUSCULAR
Effective Date
9/23/2026
Active Ingredients
ESTRADIOL VALERATEApproval Type
Generic (ANDA)
FDA Application
ANDA216656FDA Approved
4/28/2023
TE Code
AO
On Market Since
5/1/2023
Pharmacological Classes
Price Statistics
The NADAC for ESTRADIOL VALERATE 100 MG/5 ML has been published 169 times since Jul 12, 2023, and over the history we have for it it has risen 10.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $22.6452 per ML |
|---|---|
| All-time high | $23.4442 (Mar 11, 2026) |
| All-time low | $13.5678 (Jul 17, 2024) |
| 52-week high | $23.4442 |
| 52-week low | $20.9000 |
| Median price | $21.3519 |
| Average price | $20.2880 |
| Largest weekly change | +64.9% (Aug 21, 2024) |
| Weeks tracked | 169 |
| Tracking since | Jul 12, 2023 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Estradiol valerate market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Xiromed LLC manufacturer profile
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Drug market
Estradiol valerate market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Estrogen class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
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Frequently asked questions
What is the NADAC price of ESTRADIOL VALERATE 100 MG/5 ML?
The current National Average Drug Acquisition Cost (NADAC) for ESTRADIOL VALERATE 100 MG/5 ML, manufactured by Xiromed LLC, is $22.6452 per ML (NDC 70700027422), effective Sep 30, 2026.
How has the price of ESTRADIOL VALERATE 100 MG/5 ML changed over time?
Over the history we have for it, the NADAC for ESTRADIOL VALERATE 100 MG/5 ML has risen 10.7%. It has been tracked across 169 weekly CMS publications since Jul 12, 2023.
What are the highest and lowest recorded NADAC prices for ESTRADIOL VALERATE 100 MG/5 ML?
Since Jul 12, 2023, the NADAC for ESTRADIOL VALERATE 100 MG/5 ML has ranged from a low of $13.5678 (Jul 17, 2024) to a high of $23.4442 (Mar 11, 2026), with a median of $21.3519 per ML.
Are there cheaper alternatives to ESTRADIOL VALERATE 100 MG/5 ML?
No other NADAC-published product currently shares the active ingredient and strength of ESTRADIOL VALERATE 100 MG/5 ML in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures ESTRADIOL VALERATE 100 MG/5 ML?
ESTRADIOL VALERATE 100 MG/5 ML (NDC 70700027422) is labeled by Xiromed LLC, and CMS classifies it as a generic product.