Product Information

CLOBETASOL 0.05% CREAM is a generic product labeled by NorthStar Rx LLC, priced at $0.1884 per GM under NDC 72603032301. Its NADAC has been published 77 times since Mar 5, 2025.

FDA first approved this application on Aug 28, 2020. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

CLOBETASOL 0.05% CREAM

Clobetasol Propionate Cream USP, 0.05%
$0.1884per GM

Strength

.5 mg/g

Manufacturer

NorthStar Rx LLC

NDC

72603032301

Classification

Generic

Dosage Form

CREAM

Route

TOPICAL

Effective Date

8/19/2026

Active Ingredients

CLOBETASOL PROPIONATE

Approval Type

Generic (ANDA)

FDA Application

ANDA212982

FDA Approved

8/28/2020

TE Code

AB1

On Market Since

11/1/2024

Pharmacological Classes

Corticosteroid Hormone Receptor Agonists
Corticosteroid

Price Statistics

The NADAC for CLOBETASOL 0.05% CREAM has been published 77 times since Mar 5, 2025, and over the history we have for it it has risen 9.5%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1884 per GM
All-time high$0.1884 (Aug 19, 2026)
All-time low$0.1721 (Mar 5, 2025)
52-week high$0.1884
52-week low$0.1787
Median price$0.1815
Average price$0.1806
Largest weekly change+4.1% (Mar 19, 2025)
Weeks tracked77
Tracking sinceMar 5, 2025

Price History

1W

+2.4%

1M

+2.4%

3M

+3.3%

6M

+2.3%

1Y

+2.2%

3Y

N/A

5Y

N/A

All

+9.5%

Generic Alternatives

The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 39% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of CLOBETASOL 0.05% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL 0.05% CREAM, manufactured by NorthStar Rx LLC, is $0.1884 per GM (NDC 72603032301), effective Aug 19, 2026.

How has the price of CLOBETASOL 0.05% CREAM changed over time?

Over the history we have for it, the NADAC for CLOBETASOL 0.05% CREAM has risen 9.5%. It has been tracked across 77 weekly CMS publications since Mar 5, 2025.

What are the highest and lowest recorded NADAC prices for CLOBETASOL 0.05% CREAM?

Since Mar 5, 2025, the NADAC for CLOBETASOL 0.05% CREAM has ranged from a low of $0.1721 (Mar 5, 2025) to a high of $0.1884 (Aug 19, 2026), with a median of $0.1815 per GM.

Are there cheaper alternatives to CLOBETASOL 0.05% CREAM?

Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CLOBETASOL 0.05% CREAM, is $0.1158 per GM — about 39% below CLOBETASOL 0.05% CREAM.

Who manufactures CLOBETASOL 0.05% CREAM?

CLOBETASOL 0.05% CREAM (NDC 72603032301) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.