Product Information
LIDOCAINE HCL 2% 400 MG/20 ML is a generic product labeled by NorthStar Rx LLC, priced at $0.0796 per ML under NDC 72603074425. Its NADAC has been published 56 times since Jul 30, 2025.
FDA first approved this application on Nov 8, 2021. Its Orange Book therapeutic-equivalence code is AP.
Strength
20 mg/mL
Manufacturer
NorthStar Rx LLCNDC
72603074425
Classification
Generic
Dosage Form
INJECTION, SOLUTION
Route
INFILTRATION; PERINEURAL
Effective Date
8/19/2026
Active Ingredients
LIDOCAINE HYDROCHLORIDE ANHYDROUSApproval Type
Generic (ANDA)
FDA Application
ANDA214336FDA Approved
11/8/2021
TE Code
AP
On Market Since
2/1/2025
Pharmacological Classes
Price Statistics
The NADAC for LIDOCAINE HCL 2% 400 MG/20 ML has been published 56 times since Jul 30, 2025, and over the history we have for it it has declined 3.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0796 per ML |
|---|---|
| All-time high | $0.0902 (Jun 10, 2026) |
| All-time low | $0.0796 (Aug 19, 2026) |
| 52-week high | $0.0902 |
| 52-week low | $0.0796 |
| Median price | $0.0859 |
| Average price | $0.0859 |
| Largest weekly change | -7.3% (Aug 19, 2026) |
| Weeks tracked | 56 |
| Tracking since | Jul 30, 2025 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of LIDOCAINE HCL 2% 400 MG/20 ML?
The current National Average Drug Acquisition Cost (NADAC) for LIDOCAINE HCL 2% 400 MG/20 ML, manufactured by NorthStar Rx LLC, is $0.0796 per ML (NDC 72603074425), effective Aug 19, 2026.
How has the price of LIDOCAINE HCL 2% 400 MG/20 ML changed over time?
Over the history we have for it, the NADAC for LIDOCAINE HCL 2% 400 MG/20 ML has declined 3.7%. It has been tracked across 56 weekly CMS publications since Jul 30, 2025.
What are the highest and lowest recorded NADAC prices for LIDOCAINE HCL 2% 400 MG/20 ML?
Since Jul 30, 2025, the NADAC for LIDOCAINE HCL 2% 400 MG/20 ML has ranged from a low of $0.0796 (Aug 19, 2026) to a high of $0.0902 (Jun 10, 2026), with a median of $0.0859 per ML.
Are there cheaper alternatives to LIDOCAINE HCL 2% 400 MG/20 ML?
2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as LIDOCAINE HCL 2% 400 MG/20 ML in a comparable dosage form, but none are currently priced below it.
Who manufactures LIDOCAINE HCL 2% 400 MG/20 ML?
LIDOCAINE HCL 2% 400 MG/20 ML (NDC 72603074425) is labeled by NorthStar Rx LLC, and CMS classifies it as a generic product.