Product Information
TRAMADOL HCL 50 MG TABLET is a generic product labeled by Advagen Pharma Ltd., priced at $0.0245 per EA under NDC 72888008005. Its NADAC has been published 237 times since Feb 9, 2022.
FDA first approved this application on Jun 28, 2019. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/1
Manufacturer
Advagen Pharma Ltd.NDC
72888008005
Classification
Generic
Dosage Form
TABLET, COATED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
TRAMADOL HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA208708FDA Approved
6/28/2019
TE Code
AB
On Market Since
7/24/2023
Pharmacological Classes
Price Statistics
The NADAC for TRAMADOL HCL 50 MG TABLET has been published 237 times since Feb 9, 2022, and over the history we have for it it has risen 2.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0245 per EA |
|---|---|
| All-time high | $0.0355 (Apr 10, 2024) |
| All-time low | $0.0219 (Nov 20, 2024) |
| 52-week high | $0.0254 |
| 52-week low | $0.0235 |
| Median price | $0.0251 |
| Average price | $0.0263 |
| Largest weekly change | -31.3% (Nov 20, 2024) |
| Weeks tracked | 237 |
| Tracking since | Feb 9, 2022 |
Generic Alternatives
The matcher finds 9 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 3% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of TRAMADOL HCL 50 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for TRAMADOL HCL 50 MG TABLET, manufactured by Advagen Pharma Ltd., is $0.0245 per EA (NDC 72888008005), effective Aug 19, 2026.
How has the price of TRAMADOL HCL 50 MG TABLET changed over time?
Over the history we have for it, the NADAC for TRAMADOL HCL 50 MG TABLET has risen 2.6%. It has been tracked across 237 weekly CMS publications since Feb 9, 2022.
What are the highest and lowest recorded NADAC prices for TRAMADOL HCL 50 MG TABLET?
Since Feb 9, 2022, the NADAC for TRAMADOL HCL 50 MG TABLET has ranged from a low of $0.0219 (Nov 20, 2024) to a high of $0.0355 (Apr 10, 2024), with a median of $0.0251 per EA.
Are there cheaper alternatives to TRAMADOL HCL 50 MG TABLET?
Yes. 9 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, TRAMADOL HCL 50 MG TABLET, is $0.0239 per EA — about 3% below TRAMADOL HCL 50 MG TABLET.
Who manufactures TRAMADOL HCL 50 MG TABLET?
TRAMADOL HCL 50 MG TABLET (NDC 72888008005) is labeled by Advagen Pharma Ltd., and CMS classifies it as a generic product.