Product Information
DIPHENHYDRAMINE 25 MG CAPSULE is a generic product labeled by Aarna USA Inc., priced at $0.0534 per EA under NDC 82568000402. Its NADAC has been published 36 times since Jan 28, 2026.
Strength
25 mg/1
Manufacturer
Aarna USA Inc.NDC
82568000402
Classification
Generic
Dosage Form
CAPSULE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
DIPHENHYDRAMINE HYDROCHLORIDEApproval Type
OTC MONOGRAPH DRUG
FDA Application
M012On Market Since
12/6/2024
Pharmacological Classes
Price Statistics
The NADAC for DIPHENHYDRAMINE 25 MG CAPSULE has been published 36 times since Jan 28, 2026, and over the history we have for it it has declined 16.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0534 per EA |
|---|---|
| All-time high | $0.0640 (Feb 11, 2026) |
| All-time low | $0.0534 (Sep 23, 2026) |
| 52-week high | $0.0640 |
| 52-week low | $0.0534 |
| Median price | $0.0604 |
| Average price | $0.0588 |
| Largest weekly change | -5.2% (Jun 17, 2026) |
| Weeks tracked | 36 |
| Tracking since | Jan 28, 2026 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 42% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Aarna USA Inc. manufacturer profile
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Drug market
Diphenhydramine HCl market comparison
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Therapeutic class
Histamine-1 Receptor Antagonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of DIPHENHYDRAMINE 25 MG CAPSULE?
The current National Average Drug Acquisition Cost (NADAC) for DIPHENHYDRAMINE 25 MG CAPSULE, manufactured by Aarna USA Inc., is $0.0534 per EA (NDC 82568000402), effective Sep 30, 2026.
How has the price of DIPHENHYDRAMINE 25 MG CAPSULE changed over time?
Over the history we have for it, the NADAC for DIPHENHYDRAMINE 25 MG CAPSULE has declined 16.6%. It has been tracked across 36 weekly CMS publications since Jan 28, 2026.
What are the highest and lowest recorded NADAC prices for DIPHENHYDRAMINE 25 MG CAPSULE?
Since Jan 28, 2026, the NADAC for DIPHENHYDRAMINE 25 MG CAPSULE has ranged from a low of $0.0534 (Sep 23, 2026) to a high of $0.0640 (Feb 11, 2026), with a median of $0.0604 per EA.
Are there cheaper alternatives to DIPHENHYDRAMINE 25 MG CAPSULE?
Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DIPHENHYDRAMINE 25 MG CAPSULE, is $0.0311 per EA — about 42% below DIPHENHYDRAMINE 25 MG CAPSULE.
Who manufactures DIPHENHYDRAMINE 25 MG CAPSULE?
DIPHENHYDRAMINE 25 MG CAPSULE (NDC 82568000402) is labeled by Aarna USA Inc., and CMS classifies it as a generic product.