Product Information

DIPHENHYDRAMINE 25 MG CAPSULE is a generic product labeled by Aarna USA Inc., priced at $0.0542 per EA under NDC 82568000402. Its NADAC has been published 30 times since Jan 28, 2026.

DIPHENHYDRAMINE 25 MG CAPSULE

Diphenhydramine HCl
$0.0542per EA
OTC

Strength

25 mg/1

Manufacturer

Aarna USA Inc.

NDC

82568000402

Classification

Generic

Dosage Form

CAPSULE

Route

ORAL

Effective Date

8/19/2026

Approval Type

OTC MONOGRAPH DRUG

FDA Application

M012

On Market Since

12/6/2024

Pharmacological Classes

Histamine H1 Receptor Antagonists
Histamine-1 Receptor Antagonist

Price Statistics

The NADAC for DIPHENHYDRAMINE 25 MG CAPSULE has been published 30 times since Jan 28, 2026, and over the history we have for it it has declined 15.3%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0542 per EA
All-time high$0.0640 (Feb 11, 2026)
All-time low$0.0542 (Aug 19, 2026)
52-week high$0.0640
52-week low$0.0542
Median price$0.0605
Average price$0.0598
Largest weekly change-5.2% (Jun 17, 2026)
Weeks tracked30
Tracking sinceJan 28, 2026

Price History

1W

-2.8%

1M

-2.8%

3M

-10.3%

6M

-12.4%

1Y

N/A

3Y

N/A

5Y

N/A

All

-15.3%

Generic Alternatives

The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 43% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of DIPHENHYDRAMINE 25 MG CAPSULE?

The current National Average Drug Acquisition Cost (NADAC) for DIPHENHYDRAMINE 25 MG CAPSULE, manufactured by Aarna USA Inc., is $0.0542 per EA (NDC 82568000402), effective Aug 19, 2026.

How has the price of DIPHENHYDRAMINE 25 MG CAPSULE changed over time?

Over the history we have for it, the NADAC for DIPHENHYDRAMINE 25 MG CAPSULE has declined 15.3%. It has been tracked across 30 weekly CMS publications since Jan 28, 2026.

What are the highest and lowest recorded NADAC prices for DIPHENHYDRAMINE 25 MG CAPSULE?

Since Jan 28, 2026, the NADAC for DIPHENHYDRAMINE 25 MG CAPSULE has ranged from a low of $0.0542 (Aug 19, 2026) to a high of $0.0640 (Feb 11, 2026), with a median of $0.0605 per EA.

Are there cheaper alternatives to DIPHENHYDRAMINE 25 MG CAPSULE?

Yes. 3 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DIPHENHYDRAMINE 25 MG CAPSULE, is $0.0311 per EA — about 43% below DIPHENHYDRAMINE 25 MG CAPSULE.

Who manufactures DIPHENHYDRAMINE 25 MG CAPSULE?

DIPHENHYDRAMINE 25 MG CAPSULE (NDC 82568000402) is labeled by Aarna USA Inc., and CMS classifies it as a generic product.